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Ambulatory blood pressure abnormalities in children with migraine

偏头痛儿童的动态血压异常

  • 影响因子:2.09
  • DOI:10.1007/s00467-020-04640-1
  • 作者列表:"Yılmaz, Songül","Özlü, Sare Gülfem","Kurt, Ayşegül Neşe Çıtak
  • 发表时间:2020-06-17
Abstract

Background Although there are data showing that the frequency of hypertension increases in adults with migraine, there has been no study on this subject in children. In this study, we aimed to evaluate the presence of hypertension in children with migraine by performing ambulatory blood pressure monitoring (ABPM). Methods Thirty-seven children diagnosed with migraine and 30 healthy controls were evaluated between January 2015 and March 2016. Demographic data, clinical and laboratory features, and physical examination findings were recorded for both groups. Office blood pressure was measured for all children, and each also underwent ABPM. The two groups were compared in terms of ambulatory blood pressure parameters. Results The mean age was 13.3 and 13.1 years and the proportion of females was 73% and 60% in the migraine and control groups, respectively. Although the frequency of hypertension was not higher, abnormal ABPM patterns were found to be significantly more frequent in the migraine group (migraine, 45.9%; control, 16.7%; p , 0.018). Nighttime mean arterial blood pressure, nighttime diastolic blood pressure, and non-dipping pattern were higher in children with migraine than those in the control group ( p < 0.05). Conclusions These results suggest that ambulatory blood pressure abnormalities may be present in almost half of patients with migraine. Therefore, we suggest that ABPM should be performed even if the office blood pressure measurements of children diagnosed with migraine are normal.

摘要

背景虽然有数据显示成人偏头痛患者高血压的频率增加,但尚未有关于这一主题在儿童中的研究。在这项研究中,我们旨在通过进行动态血压监测 (ABPM) 来评估偏头痛患儿是否存在高血压。方法对 2015 年 1 月至 2016 年 3 月确诊为偏头痛的 37 例儿童和 30 名健康对照者进行评价。记录两组的人口统计学数据、临床和实验室特征以及体格检查结果。测量所有儿童的办公室血压,每个儿童也接受了 ABPM。比较两组患者的动态血压参数。结果偏头痛组和对照组的平均年龄分别为 13.3 岁和 13.1 岁,女性比例分别为 73% 和 60%。虽然高血压的频率并不高,但发现异常 ABPM 模式在偏头痛组中明显更频繁 (偏头痛,45.9%; 对照,16.7%; p,0.018)。偏头痛患儿夜间平均动脉压、夜间舒张压、非浸渍型均高于对照组 (p <0.05)。结论这些结果表明,几乎一半的偏头痛患者可能存在动态血压异常。因此,我们建议即使诊断为偏头痛的儿童的办公室血压测量正常,也应进行 ABPM。

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