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Validation and Cardiorespiratory Response of the 1-min Sit-to-Stand Test in Interstitial Lung Disease.

间质性肺疾病 1 min 坐位试验的验证和心肺反应。

  • 影响因子:4.34
  • DOI:10.1249/MSS.0000000000002423
  • 作者列表:"Labrecque PT","Harvey J","Nadreau É","Maltais F","Dion G","Saey D
  • 发表时间:2020-06-15
Abstract

PURPOSE:To assess the 1STS test-retest reliability and construct validity and its associated cardiorespiratory response in comparison to the 6-minute walk test (6MWT) and symptom-limited cycling cardiopulmonary exercise test (CPET) in people with interstitial lung disease (ILD). METHODS:15 participants with ILD performed two 1STS tests, a 6MWT and a CPET. The three tests were administered on three separate visits and cardiorespiratory parameters were continuously recorded during the tests. RESULTS:The number of repetitions during both 1STS tests was 22 ± 4 and 22 ± 4 (mean difference of 0.53 ± 2.00 repetitions, p=0.32) with an intraclass correlation of 0.937 (95%CI [0.811; 0.979]) and a minimal detectable change of 2.9 repetitions. The number of 1STS repetitions was highly correlated with the 6MWT distance (r = 0.823, p<0.001) and with the peak cycling power output expressed in % predicted values (r = 0.706, p<0.003). Oxygen consumption (V˙O2) peak during the 1STS reached 83% and 78% of V˙O2 peak during 6MWT and CPET, respectively. Peak 1STS heart rate (HR), minute ventilation (V˙E,), V˙O2 values as well nadir SpO2 were achieved during the recovery phase of the test while peak 6MWT and CPET HR, V˙E, V˙O2 and nadir SpO2 always occurred at the end of the test. The three tests elicited a similar fall in SpO2 ranging between 8-12%. Symptom scores after the 1STS were similar to those seen at the end of the 6MWT but lower than those of CPET. CONCLUSION:The 1STS showed excellent test-retest reliability in patients with ILD in whom it elicited a substantial, but submaximal cardiorespiratory response. Our data also support the construct validity of the 1STS to assess functional exercise capacity in patients with ILD and to detect exercise-induced O2 desaturation.

摘要

目的: 与 6 分钟步行试验 (6MWT) 相比,评估 1STS 重测信度和结构效度及其相关的心肺反应间质性肺病 (ILD) 患者的症状限制性循环心肺运动试验 (CPET)。 方法: 15 例 ILD 参与者进行了两次 1STS 试验,一次 6MWT,一次 CPET。三次试验分别进行三次访视,试验期间连续记录心肺参数。 结果: 两次 1STS 测试的重复次数分别为 22 ± 4 和 22 ± 4 (0.53 ± 2.00 次重复的平均差异,p = 0.32) 组内相关性为 0.937 (95% CI [0.811; 0.979]),最小可检测变化为 2.9 次重复。1STS 重复次数与 6MWT 距离高度相关 (r = 0.823,p<0.001),与峰值循环功率输出以 % 预测值表示 (r = 0.706, p<0.003)。1STS 期间的耗氧量 (v O2) 峰值分别达到 6MWT 和 CPET 期间 v O2 峰值的 83% 和 78%。在试验恢复期达到峰值 1STS 心率 (HR) 、分钟通气量 (ve) 、 vo2 值以及最低值 SpO2,而峰值 6MWT 和 CPET HR 、 ve 、试验结束时总是出现血氧饱和度和血氧饱和度最低值。三次测试引起 SpO2 在 8-12% 之间的类似下降。1STS 后的症状评分与 6MWT 结束时的症状评分相似,但低于 CPET。 结论: 1STS 在 ILD 患者中显示出极好的重测信度,在这些患者中,它引起了大量但次最大的心肺反应。我们的数据也支持 1STS 评估 ILD 患者功能运动能力和检测运动诱导的 O2 去饱和的结构有效性。

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翻译标题与摘要 下载文献
影响因子:4.40
发表时间:2020-01-01
DOI:10.1007/s00262-019-02431-8
作者列表:["Shibaki, Ryota","Murakami, Shuji","Matsumoto, Yuji","Yoshida, Tatsuya","Goto, Yasushi","Kanda, Shintaro","Horinouchi, Hidehito","Fujiwara, Yutaka","Yamamoto, Nobuyuki","Kusumoto, Masahiko","Yamamoto, Noboru","Ohe, Yuichiro"]

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翻译标题与摘要 下载文献
影响因子:4.04
发表时间:2020-01-25
来源期刊:New biotechnology
DOI:10.1016/j.nbt.2019.08.006
作者列表:["Sousa SA","Soares-Castro P","Seixas AMM","Feliciano JR","Balugas B","Barreto C","Pereira L","Santos PM","Leitão JH"]

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