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Kaposi's sarcoma in a HIV-positive patient: an exuberant and widespread case report in the Amazon.

1 例HIV阳性患者的卡波西肉瘤: 亚马逊一个旺盛而广泛的病例报告。

  • 影响因子:1.39
  • DOI:10.1590/S1678-9946202062002
  • 作者列表:"Pires CAA","Monteiro JCMS","Rego RM","Lodi VJC
  • 发表时间:2020-01-17
Abstract

:A 37-year-old male patient, Fitzpatrick skin phototype IV, a student living in Belem, Amazon region, in 2015 had a confirmed diagnosis of acquired immunodeficiency virus (HIV) infection, but did not initiate antiretroviral treatment at his own option. Three years after the diagnosis, erythematous maculae appeared on the dorsum of the nose with rapid progression to the entire face, with posterior diffuse infiltration and appearance of nodules on the chin and shoulder. In December 2018, the patient presented with exacerbation of the condition with an increase in infiltrated violaceous plaques and disseminated violaceous nodules. A histopathological biopsy of the skin was performed, confirming the diagnosis of angiomatoid proliferation suggestive of Kaposi's sarcoma (KS), with an important dissemination of this disease to the noble organs. In addition, it is important to note that he only started antiretroviral therapy (ART) after the exacerbation of Kaposi (December 2018). In such cases, chemotherapy associated with ART is crucial for the treatment and follow-up of the patient, since Kaposi's sarcoma develops relatively low in patients who do not have immunodeficiency.

摘要

: 一名 37 岁的男性患者,Fitzpatrick skin phototype IV,一名居住在亚马逊地区贝伦的学生,2015 年确诊为获得性免疫缺陷病毒 (HIV) 感染,但他没有自主选择启动抗逆转录病毒治疗。诊断后 3 年,鼻背出现红斑斑疹,迅速进展至整个面部,后弥漫性浸润,下巴和肩部出现结节。2018 年 12 月,患者出现病情恶化,浸润的紫罗兰色斑块和播散性紫罗兰色结节增加。进行了皮肤组织病理学活检,证实诊断为血管瘤样增生,提示卡波西肉瘤 (KS),该病重要播散至正常器官。此外,重要的是要注意,他在卡波西恶化 (2018 年 12 月) 后才开始抗逆转录病毒治疗 (ART)。在这种情况下,与ART相关的化疗对于患者的治疗和随访至关重要,因为卡波西肉瘤在没有免疫缺陷的患者中发展相对较低。

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皮肤肿瘤方向

皮肤肿瘤是发生在皮肤的细胞增生性疾病,是一种常见病。发生于皮内或皮下组织的新生物,种类很多,临床上分良性肿瘤和恶性肿瘤。恶性肿瘤可以不断增殖,引起转移,威胁生命,称为皮肤癌。

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