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Diagnosis and Management of Pediatric Influenza in the Era of Rapid Diagnostics.

快速诊断时代小儿流感的诊断和管理。

  • 影响因子:1.82
  • DOI:10.1093/jpids/piy118
  • 作者列表:"Kitt E","Drew RJ","Cunney R","Beekmann SE","Polgreen P","Butler K","Zaoutis T","Coffin SE
  • 发表时间:2020-02-28
Abstract

:Influenza is a significant cause of childhood morbidity and death; it contributes to up to 16% of hospitalizations for respiratory illnesses worldwide. Novel rapid viral diagnostic tests, including molecular diagnostic tests, have the potential to significantly affect both time to diagnosis and selection of optimal anti-infective therapy. However, little is known about current treatment algorithms used in US hospitals. In this study, for hospitalized children in the United States, we aimed to define the current approaches to influenza diagnosis and treatment and to explore reasons for their potential variation. In this study, we aimed to define the current approaches to pediatric influenza diagnosis and treatment in US hospitals, and to explore reasons for their potential variation. Our results suggest a rise in the availability and use of rapid molecular diagnostic testing in addition to continued variability in anti-infective management, particularly with regard to antiviral use.

摘要

: 流感是儿童发病和死亡的重要原因; 它导致了全球高达 16% 的呼吸系统疾病住院。新型快速病毒诊断试验,包括分子诊断试验,有可能显著影响诊断时间和最佳抗感染治疗的选择。然而,目前对美国医院使用的治疗算法知之甚少。在这项研究中,对于美国的住院儿童,我们旨在定义当前的流感诊断和治疗方法,并探讨其潜在变异的原因。在这项研究中,我们旨在定义目前美国医院儿科流感诊断和治疗的方法,并探讨其潜在变异的原因。我们的结果表明,除了抗感染管理的持续变异性,特别是在抗病毒使用方面,快速分子诊断检测的可用性和使用有所增加。

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DOI:10.3346/jkms.2020.35.e79
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翻译标题与摘要 下载文献
影响因子:2.48
发表时间:2020-04-01
来源期刊:Infection
DOI:10.1007/s15010-020-01401-y
作者列表:["Cheng ZJ","Shan J"]

METHODS::There is a current worldwide outbreak of a new type of coronavirus (2019-nCoV), which originated from Wuhan in China and has now spread to 17 other countries. Governments are under increased pressure to stop the outbreak spiraling into a global health emergency. At this stage, preparedness, transparency, and sharing of information are crucial to risk assessments and beginning outbreak control activities. This information should include reports from outbreak sites and from laboratories supporting the investigation. This paper aggregates and consolidates the virology, epidemiology, clinical management strategies from both English and Chinese literature, official news channels, and other official government documents. In addition, by fitting the number of infections with a single-term exponential model, we report that the infection is spreading at an exponential rate, with a doubling period of 1.8 days.

呼吸道感染方向

呼吸道感染分为上呼吸道感染与下呼吸道感染。上呼吸道感染是指自鼻腔至喉部之间的急性炎症的总称,是最常见的感染性疾病。下呼吸道感染是最常见的感染性疾患,治疗时必须明确引起感染的病原体以选择有效的抗生素。

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