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Clinical and CT features in pediatric patients with COVID-19 infection: Different points from adults.

儿童新型冠状病毒肺炎感染的临床和CT特征: 与成人的不同点。

  • 影响因子:2.38
  • DOI:10.1002/ppul.24718
  • 作者列表:"Xia W","Shao J","Guo Y","Peng X","Li Z","Hu D
  • 发表时间:2020-05-01
Abstract

PURPOSE:To discuss the different characteristics of clinical, laboratory, and chest computed tomography (CT) in pediatric patients from adults with 2019 novel coronavirus (COVID-19) infection. METHODS:The clinical, laboratory, and chest CT features of 20 pediatric inpatients with COVID-19 infection confirmed by pharyngeal swab COVID-19 nucleic acid test were retrospectively analyzed during 23 January and 8 February 2020. The clinical and laboratory information was obtained from inpatient records. All the patients were undergone chest CT in our hospital. RESULTS:Thirteen pediatric patients (13/20, 65%) had an identified history of close contact with COVID-19 diagnosed family members. Fever (12/20, 60%) and cough (13/20, 65%) were the most common symptoms. For laboratory findings, procalcitonin elevation (16/20, 80%) should be pay attention to, which is not common in adults. Coinfection (8/20, 40%) is common in pediatric patients. A total of 6 patients presented with unilateral pulmonary lesions (6/20, 30%), 10 with bilateral pulmonary lesions (10/20, 50%), and 4 cases showed no abnormality on chest CT (4/20, 20%). Consolidation with surrounding halo sign was observed in 10 patients (10/20, 50%), ground-glass opacities were observed in 12 patients (12/20, 60%), fine mesh shadow was observed in 4 patients (4/20, 20%), and tiny nodules were observed in 3 patients (3/20, 15%). CONCLUSION:Procalcitonin elevation and consolidation with surrounding halo signs were common in pediatric patients which were different from adults. It is suggested that underlying coinfection may be more common in pediatrics, and the consolidation with surrounding halo sign which is considered as a typical sign in pediatric patients.

摘要

目的: 探讨 2019 例成人新型冠状病毒 (新型冠状病毒肺炎) 感染患儿的临床、实验室和胸部CT表现。 方法: 回顾性分析实验室,胸部CT表现 20 儿科住院患者新型冠状病毒肺炎感染证实咽拭子新型冠状病毒肺炎核酸test回顾性分析 23 日和 8 日 2020 年.临床和实验室信息来自住院记录。所有患者均在我院行胸部CT检查。 结果: 13 例儿童患者 (13/20,65%) 有明确的密切接触者史,新型冠状病毒肺炎诊断为家庭成员。发热 (12/20,60%) 和咳嗽 (13/20,65%) 是最常见的症状。对于实验室发现,应注意降钙素原升高 (16/20,80%),成人不常见。合并感染 (8/20,40%) 在儿科患者中很常见。共有 6 例患者表现为单侧肺部病变 (6/20,30%),10 例表现为双侧肺部病变 (10/20,50%),和 4 例未见异常,胸部CT (4/20,20%).巩固与周围晕征到 10 例 (10/20,50%),磨玻璃影观察 12 例 (12/20,60%),4 例 (4/20,20%) 观察到细网影,3 例 (3/20,15%) 观察到微小结节。 结论: 降钙素原升高及合并周围晕征在儿科患者中常见,与成人不同。提示潜在的合并感染在儿科可能更常见,合并周围晕征被认为是儿科患者的典型体征。

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翻译标题与摘要 下载文献
影响因子:2.48
发表时间:2020-04-01
来源期刊:Infection
DOI:10.1007/s15010-020-01401-y
作者列表:["Cheng ZJ","Shan J"]

METHODS::There is a current worldwide outbreak of a new type of coronavirus (2019-nCoV), which originated from Wuhan in China and has now spread to 17 other countries. Governments are under increased pressure to stop the outbreak spiraling into a global health emergency. At this stage, preparedness, transparency, and sharing of information are crucial to risk assessments and beginning outbreak control activities. This information should include reports from outbreak sites and from laboratories supporting the investigation. This paper aggregates and consolidates the virology, epidemiology, clinical management strategies from both English and Chinese literature, official news channels, and other official government documents. In addition, by fitting the number of infections with a single-term exponential model, we report that the infection is spreading at an exponential rate, with a doubling period of 1.8 days.

呼吸道感染方向

呼吸道感染分为上呼吸道感染与下呼吸道感染。上呼吸道感染是指自鼻腔至喉部之间的急性炎症的总称,是最常见的感染性疾病。下呼吸道感染是最常见的感染性疾患,治疗时必须明确引起感染的病原体以选择有效的抗生素。

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