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Mid-term survivorship and patient-reported outcomes of robotic-arm assisted partial knee arthroplasty.

机器人手臂辅助部分膝关节置换术的中期生存率和患者报告结局。

  • 影响因子:0
  • DOI:10.1302/0301-620X.102B1.BJJ-2019-0510.R1
  • 作者列表:"Burger JA","Kleeblad LJ","Laas N","Pearle AD
  • 发表时间:2020-01-01
Abstract

AIMS:Limited evidence is available on mid-term outcomes of robotic-arm assisted (RA) partial knee arthroplasty (PKA). Therefore, the purpose of this study was to evaluate mid-term survivorship, modes of failure, and patient-reported outcomes of RA PKA. METHODS:A retrospective review of patients who underwent RA PKA between June 2007 and August 2016 was performed. Patients received a fixed-bearing medial or lateral unicompartmental knee arthroplasty (UKA), patellofemoral arthroplasty (PFA), or bicompartmental knee arthroplasty (BiKA; PFA plus medial UKA). All patients completed a questionnaire regarding revision surgery, reoperations, and level of satisfaction. Knee Injury and Osteoarthritis Outcome Scores (KOOS) were assessed using the KOOS for Joint Replacement Junior survey. RESULTS:Mean follow-up was 4.7 years (2.0 to 10.8). Five-year survivorship of medial UKA (n = 802), lateral UKA (n = 171), and PFA/BiKA (n = 35/10) was 97.8%, 97.7%, and 93.3%, respectively. Component loosening and progression of osteoarthritis (OA) were the most common reasons for revision. Mean KOOS scores after medial UKA, lateral UKA, and PFA/BiKA were 84.3 (SD 15.9), 85.6 (SD 14.3), and 78.2 (SD 14.2), respectively. The vast majority of the patients reported high satisfaction levels after RA PKA. Subgroup analyses suggested tibial component design, body mass index (BMI), and age affects RA PKA outcomes. Five-year survivorship was 98.4% (95% confidence interval (CI) 97.2 to 99.5) for onlay medial UKA (n = 742) and 99.1% (95% CI 97.9 to 100) for onlay medial UKA in patients with a BMI < 30 kg/m2 (n = 479). CONCLUSION:This large single-surgeon study showed high mid-term survivorship, satisfaction levels, and functional outcomes in RA UKA using metal-backed tibial onlay components. In addition, favourable results were reported in RA PFA and BiKA. Cite this article: Bone Joint J 2020;102-B(1):108-116.

摘要

目的: 关于机器人手臂辅助 (RA) 部分膝关节置换术 (PKA) 的中期结果证据有限。因此,本研究的目的是评估RA PKA的中期生存率、失败模式和患者报告结局。 方法: 回顾性分析 2007 年 6 月至 2016 年 8 月期间接受RA PKA的患者。患者接受固定承重的内侧或外侧单髁膝关节置换术 (UKA) 、髌股关节置换术 (PFA) 或双髁膝关节置换术 (BiKA; PFA加内侧UKA)。所有患者均完成了关于翻修手术、再手术和满意度水平的问卷调查。使用用于关节置换初级调查的KOOS评估膝关节损伤和骨关节炎结局评分 (KOOS)。 结果: 平均随访 4.7 年 (2.0 ~ 10.8)。内侧UKA (n = 802) 、外侧UKA (n = 171) 和PFA/BiKA (n = 35/10) 的 5 年生存率分别为 97.8% 、 97.7% 和 93.3%。骨性关节炎 (OA) 的成分松动和进展是翻修的最常见原因。内侧UKA、外侧UKA和PFA/BiKA后的平均KOOS评分分别为 84.3 (SD 15.9) 、 85.6 (SD 14.3) 和 78.2 (SD 14.2)。绝大多数患者报告RA PKA后满意度高。亚组分析提示胫骨成分设计、体重指数 (BMI) 和年龄影响RA PKA结局。Onlay内侧UKA (n = 98.4%) 的五年生存率为 95% (97.2 置信区间 (CI) 99.5 至 742) 和 99.1% (95% CI 97.9 至 100) 对于BMI <30千克kg/m2 (n = 479) 的患者,onlay内侧UKA。 结论: 这项大型单外科医生研究显示,使用金属支持胫骨支架组件的RA UKA的中期生存率、满意度和功能结局较高。此外,在RA PFA和BiKA中报告了有利的结果。引用本文: 骨关节J 2020;1 02-B(1):1 08-1 1 6.

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影响因子:4.13
发表时间:2020-01-01
DOI:10.1002/acr.23824
作者列表:["Chen SK","Liao KP","Liu J","Kim SC"]

METHODS:OBJECTIVE:We aimed to evaluate the comparative risk of hospitalized infection among patients with rheumatoid arthritis (RA) who initiated abatacept versus a tumor necrosis factor inhibitor (TNFi). METHODS:Using claims data from Truven MarketScan database (2006-2015), we identified patients with RA ages ≥18 years with ≥2 RA diagnoses who initiated treatment with abatacept or a TNFi. The primary outcome was a composite end point of any hospitalized infection. Secondary outcomes included bacterial infection, herpes zoster, and infections affecting different organ systems. We performed 1:1 propensity score (PS) matching between the groups in order to control for baseline confounders. We estimated incidence rates (IRs) and hazard ratios (HRs) with 95% confidence intervals (95% CIs) for hospitalized infection. RESULTS:We identified 11,248 PS-matched pairs of patients who initiated treatment with abatacept and TNFi with a median age of 56 years (83% were women). The IR per 1,000 person-years for any hospitalized infection was 37 among patients who initiated treatment with abatacept and 47 in those who initiated treatment with TNFi. The HR for the risk of any hospitalized infection associated with abatacept versus TNFi was 0.78 (95% CI 0.64-0.95) and remained lower when compared to infliximab (HR 0.63 [95% CI 0.47-0.85]), while no significant difference was seen when compared to adalimumab and etanercept. The risk of secondary outcomes was lower for abatacept for pulmonary infections, and similar to TNFi for the remaining outcomes. CONCLUSION:In this large cohort of patients with RA who initiated treatment with abatacept or TNFi as a first- or second-line biologic agent, we found a lower risk of hospitalized infection after initiating abatacept versus TNFi, which was driven mostly by infliximab.

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影响因子:4.13
发表时间:2020-01-01
DOI:10.1002/acr.23827
作者列表:["Lee RR","Rashid A","Thomson W","Cordingley L"]

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