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A mitochondrial genetic divergence proxy predicts the reproductive compatibility of mammalian hybrids.

线粒体遗传分歧代理预测哺乳动物杂种的生殖相容性。

  • 影响因子:4.72
  • DOI:10.1098/rspb.2020.0690
  • 作者列表:"Allen R","Ryan H","Davis BW","King C","Frantz L","Irving-Pease E","Barnett R","Linderholm A","Loog L","Haile J","Lebrasseur O","White M","Kitchener AC","Murphy WJ","Larson G
  • 发表时间:2020-06-10
Abstract

:Numerous pairs of evolutionarily divergent mammalian species have been shown to produce hybrid offspring. In some cases, F1 hybrids are able to produce F2s through matings with F1s. In other instances, the hybrids are only able to produce offspring themselves through backcrosses with a parent species owing to unisexual sterility (Haldane's Rule). Here, we explicitly tested whether genetic distance, computed from mitochondrial and nuclear genes, can be used as a proxy to predict the relative fertility of the hybrid offspring resulting from matings between species of terrestrial mammals. We assessed the proxy's predictive power using a well-characterized felid hybrid system, and applied it to modern and ancient hominins. Our results revealed a small overlap in mitochondrial genetic distance values that distinguish species pairs whose calculated distances fall within two categories: those whose hybrid offspring follow Haldane's Rule, and those whose hybrid F1 offspring can produce F2s. The strong correlation between genetic distance and hybrid fertility demonstrated here suggests that this proxy can be employed to predict whether the hybrid offspring of two mammalian species will follow Haldane's Rule.

摘要

: 许多对进化上不同的哺乳动物物种已经被证明可以产生杂交后代。在某些情况下,F1杂种能够通过与F1交配来生产F2s。在其他情况下,由于单性不育 (霍尔丹法则),杂种只能通过与亲本物种的回交产生后代。在这里,我们明确测试了从线粒体和核基因计算的遗传距离是否可以用作预测陆生哺乳动物物种之间交配导致的杂交后代相对生育力的代理。我们使用一个表征良好的felid混合系统评估了代理的预测能力,并将其应用于现代和古代人类。我们的研究结果揭示了线粒体遗传距离值的一个小的重叠,它们区分了计算距离属于两类的物种对: 那些杂交后代遵循霍尔丹法则的物种对,以及那些杂交F1后代能够产生F2s的物种对。这里证明的遗传距离和杂种生育力之间的强相关性表明,这个代理可以用来预测两个哺乳动物物种的杂种后代是否会遵循霍尔丹法则。

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DOI:10.1080/00498254.2019.1616850
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影响因子:1.27
发表时间:2020-01-01
DOI:10.1111/ppc.12392
作者列表:["Safaei Nezhad A","Ebrahimi L","Vakili MM","Kharaghani R"]

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影响因子:2.14
发表时间:2020-02-01
DOI:10.1007/s11427-019-9526-2
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