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Preoperative fall risk assessment score as a prognostic factor in gastric cancer patients after gastrectomy.

术前跌倒风险评估评分作为胃癌患者胃切除术后的预后因素。

  • 影响因子:2.04
  • DOI:10.1093/jjco/hyaa224
  • 作者列表:"Kouzu K","Tsujimoto H","Nagata H","Sugasawa H","Ishibashi Y","Hase K","Kishi Y","Ueno H
  • 发表时间:2021-04-01
Abstract

OBJECTIVE:Falls are related to frailty, which is known as an unfavorable prognosticator of gastric cancer. In this study, we investigated the influence of the fall risk assessment score on short- and long-term prognoses in patients with gastric cancer after gastrectomy. METHODS:A total of 430 patients who underwent gastrectomy for gastric cancer were included in this retrospective study. The fall risk assessment score was scored by nursing staffs on admission. We investigated the relationships between the fall risk assessment score and clinicopathological findings, postoperative outcomes and prognoses. We assigned patients with a fall risk assessment score ≥7 to the high-risk group (92 cases, 21.4%) and those with a fall risk assessment score <6 to the low-risk group (338 cases, 78.6%). RESULTS:There were no significant differences between the two groups in pathological stage of gastric cancer and postoperative complications, but the high-risk group had significantly longer postoperative hospital stays than the low-risk group (P < 0.001). The overall and the relapse-free survival rates in the high-risk group were significantly lower than those in the low-risk group. The high-risk group was one of the independent poor prognostic factors for overall survival, with a hazard ratio of 2.91 (P ≤ 0.001) in univariate analysis and a hazard ratio of 2.74 (P = 0.008) in multivariate analysis. CONCLUSIONS:While the fall risk assessment score is an objective and easy-to-use method to assess fall risk and frailty, it may present a prognostic factor in gastric cancer.

摘要

目的: 跌倒与虚弱有关,虚弱是胃癌的不良预后因素。在这项研究中,我们调查了跌倒风险评估评分对胃癌患者胃切除术后短期和长期预后的影响。 方法: 回顾性分析430例因胃癌行胃切除术患者的临床资料。入院时由护理人员进行跌倒风险评估评分。我们调查了跌倒风险评估评分与临床病理结果、术后结果和预后之间的关系。我们将跌倒风险评估评分 ≥ 7分的患者分为高危组 (92例,21.4%),将跌倒风险评估评分 <6分的患者分为低危组 (338例,78.6%)。 结果: 两组在胃癌病理分期及术后并发症方面差异无统计学意义,但高危组术后住院时间明显长于低危组 (P <0.001)。高危组的总体生存率和无复发生存率均显著低于低危组。高危组是总生存期的独立不良预后因素之一,单因素分析的风险比为2.91 (P ≤ 0.001),多因素分析的风险比为2.74 (P = 0.008)。 结论: 跌倒风险评估评分是评估胃癌患者跌倒风险和虚弱程度的一种客观且易于使用的方法,它可能是胃癌患者预后的一个因素。

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