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Prevalence of gastrointestinal nematodes, parasite control practices and anthelmintic resistance patterns in a working horse population in Egypt.

埃及工作马群体中胃肠道线虫的流行、寄生虫控制实践和驱虫抗性模式。

  • 影响因子:0
  • DOI:10.1111/evj.13325
  • 作者列表:"Salem SE","Abd El-Ghany AM","Hamad MH","Abdelaal AM","Elsheikh HA","Hamid AA","Saud MA","Daniels SP","Ras R
  • 发表时间:2021-03-01
Abstract

BACKGROUND:Anthelmintic resistance is commonly reported in horse populations in developed countries, but evidence in some working horse populations is either lacking or inconclusive. OBJECTIVES:To estimate prevalence of GI nematode infections in working horses in Egypt and to evaluate strongyle resistance to ivermectin, doramectin and fenbendazole. STUDY DESIGN:Cross-sectional study. METHODS:Faecal egg count was performed on 644 working horses from 2 provinces in Egypt. A short questionnaire about horse signalment and worming history was completed for each horse. Horses identified with ≥50 strongyle type egg/g (n = 146) underwent faecal egg count reduction testing (FECRT) following treatment with ivermectin (n = 33), doramectin (n = 33) or fenbendazole (n = 30). Risk factors for strongyle (≥200 egg/g) and Parascaris equorum (>0 egg/g) infection were investigated using multivariable logistic regression analyses. RESULTS:The prevalence of low (0-199 epg), medium (200-500 epg) and high (>500 epg) strongyle infection was 88.4%, 5.9% and 5.8%, respectively. P. equorum eggs were detected in 5.1% (n = 33) of horses. Strongyle FECR was 100%, 99.97% and 100% following treatment with ivermectin, doramectin and fenbendazole respectively. Anthelmintic treatment in the 12 months preceding examination was associated with reduced likelihood of strongyle infection (odds ratio [OR] = 0.26, 95% confidence interval [CI] = 0.14, 0.47, P < .001). The likelihood of P. equorum infection was significantly associated with horses' age (OR = 0.78, 95% CI = 0.69, 0.90; P < .001). Male horses were more likely to have P. equorum infection (OR = 2.86, 95% CI = 1.37, 5.93, P = .005). MAIN LIMITATIONS:Nonrandomised selection of study areas and larval cultures was unsuccessful for some samples. CONCLUSIONS:There were low prevalence of strongyle and P. equorum infection and no evidence of macrocyclic lactones or benzimidazole resistance in strongyles in the studied working horse population.

摘要

背景: 驱虫抗性在发达国家的马种群中普遍报道,但一些工作马种群中的证据缺乏或不确定。 目的: 评估埃及工作马中GI线虫感染的流行情况,并评估对伊维菌素、多拉菌素和芬苯达唑的免疫耐受。 研究设计: 横断面研究。 方法: 对来自埃及2个省的644匹工作马进行粪便卵计数。每匹马都完成了一份关于马信号和驱虫历史的简短问卷。在用伊维菌素 (n = 33) 、多拉菌素 (n = 33) 或芬苯达唑 (n = 30) 处理后,鉴定为 ≥ 50个strongyle型卵/g (n = 146) 的马接受粪便卵计数减少测试 (FECRT)。使用多变量logistic回归分析来调查stronyle (≥ 200 egg/g) 和副猪 (>0 egg/g) 感染的危险因素。 结果: epg低 (0 ~ 199) 、epg中 (200 ~ 500) 、epg高 (>500) 的stronyle感染率分别为88.4% 、5.9% 、5.8%。在5.1% (n = 33) 的马中检测到马卵。用伊维菌素、多拉菌素和芬苯达唑处理后,stronyle FECR分别为100% 、99.97% 和100%。检查前12个月的驱虫治疗与骨关节感染可能性降低相关 (比值比 [OR] = 0.26,95% 置信区间 [CI] = 0.14,0.47,P <.001)。马感染的可能性与马的年龄显著相关 (OR = 0.78,95% CI = 0.69,0.90; P <.001)。雄马更容易发生马P感染 (OR = 2.86,95% CI = 1.37,5.93,P = .005)。 主要限制: 研究区域和幼虫培养的非随机选择对于一些样品是不成功的。 结论: 在所研究的工作马群体中,strongyle和P. equorum感染的流行率较低,并且没有证据表明对大环内酯类或苯并咪唑具有抗性。

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