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Natural history of trigeminal neuralgia-A hospital-based retrospective study.

三叉神经痛的自然史-一项基于医院的回顾性研究。

  • 影响因子:2.28
  • DOI:10.1111/odi.13263
  • 作者列表:"Debta P","Sarode G","Sarode S","Gadbail A","Debta FM","Swain SK","Mishra E","Sahu MC
  • 发表时间:2020-04-01
Abstract

OBJECTIVE:The objective of this study was to assess the natural history of trigeminal neuralgia (TN) and pretrigeminal neuralgia (PTN) in a hospital-based sample using a retrospective and descriptive study design. METHODS:This study followed a retrospective study design, which yielded a sample size of 216 patients who were reclassified as per the new classification and diagnostic grading for practice and research proposed by the American Academy of Neurology. Based on an in-depth analysis of patient history and the treatments administered, a possible state of PTN prior to TN development was determined. RESULTS:TN shows a female predilection with predominantly unilateral involvement. A total of 45.83% of patients had left-side involvement with V3 primarily affected. Additionally, 11.11% of patients did not have any clinically apparent trigger zone, while 68.05% had a single trigger zone. Twenty-one patients were found to have suspected PTN prior to TN. The time interval between PTN onset and TN development ranged from 6 months to 6 years. The PTN pain varied, and the clinical overlap between the site of PTN and the site of future TN was 100%. CONCLUSION:An in-depth patient history can serve as a reliable modality for TN diagnosis. PTN should be considered as a differential diagnosis for pain of orofacial origin because of its overlapping features with other painful conditions.

摘要

目的: 本研究的目的是使用回顾性和描述性研究设计,在医院样本中评估三叉神经痛 (TN) 和三叉神经痛前 (PTN) 的自然病史。 方法: 本研究采用回顾性研究设计,这产生了 216 例患者的样本量,根据美国神经病学学会提出的实践和研究的新分类和诊断分级重新分类。基于对患者病史和给予的治疗的深入分析,确定了 TN 发生前 PTN 的可能状态。 结果: TN 显示女性好发,以单侧受累为主。共有 45.83% 的患者左侧受累,V3 主要受累。此外,11.11% 的患者没有任何临床上明显的触发区,而 68.05% 的患者有单一的触发区。发现 21 例患者在 TN 前疑似 PTN。PTN 发病和 TN 发展的时间间隔为 6 个月至 6 年。PTN 疼痛各不相同,PTN 部位与未来 TN 部位的临床重叠为 100%。 结论: 深入的病史可以作为 TN 诊断的可靠方法。PTN 应被认为是口面部起源疼痛的鉴别诊断疾病,因为它与其他疼痛条件重叠。

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发表时间:2020-01-29
DOI:10.1007/s11011-020-00536-z
作者列表:["Garabadu D","Singh D"]

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影响因子:4.30
发表时间:2020-01-24
来源期刊:Experimental neurology
DOI:10.1016/j.expneurol.2020.113212
作者列表:["Bertrand SJ","Zhang Z","Patel R","O'Ferrell C","Punjabi NM","Kudchadkar SR","Kannan S"]

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影响因子:1.52
发表时间:2020-01-27
来源期刊:World neurosurgery
DOI:10.1016/j.wneu.2020.01.108
作者列表:["Middlebrooks EH","Lin C","Okromelidze L","Lu CQ","Tatum WO","Wharen RE Jr","Grewal SS"]

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