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Psychological distress and quality of life following positive fecal occult blood testing in colorectal cancer screening.

结直肠癌筛查中粪便隐血试验阳性后的心理困扰和生活质量。

  • 影响因子:3.37
  • DOI:10.1002/pon.5381
  • 作者列表:"Vermeer NCA","van der Valk MJM","Snijders HS","Vasen HFA","van der Hoop AG","Guicherit OR","Liefers GJ","van de Velde CJH","Stiggelbout AM","Peeters KCMJ
  • 发表时间:2020-03-31
Abstract

OBJECTIVE:This study aimed to assess psychological functioning, quality of life, and regret about screening after a positive FIT and subsequent colonoscopy, and to evaluate changes over time. METHODS:This is a prospective cohort study. Individuals aged 55-75 with a positive Fecal Immunochemical Test (FIT) that were referred for colonoscopy between July 2017 and November 2018, were invited to complete questionnaires related to psychological distress and health-related quality of life at three pre-defined time points: before colonoscopy, after histopathology result notification, and after 6 months. Four questionnaires were used: the Psychological Consequences Questionnaire (PCQ), the 6-item Cancer Worry Scale (CWS), the Decision Regret Scale (DRS), and the 36-item Short-Form (SF-36). RESULTS:A total of 1066 participants out of 2151 eligible individuals were included. Patients with cancer showed a significant increase in psychological dysfunction (P = 0.01) and cancer worry (P = 0.008) after colonoscopy result notification, and a decline to pre-colonoscopy measurements after six months. In the no-cancer groups, psychological dysfunction and cancer worry significantly decreased over time (P < 0.05) but there was no ongoing decline. After six months, 17% of participants with no cancer experienced high level of cancer worry (CWS ≥ 10). Yet, only 5% reported high level of regret about screening participation (DRS > 25). A good global quality of life was reported in participants with no cancer. CONCLUSION:Some psychological distress remains up to six months after colonoscopy in participants who tested false-positive in the Dutch bowel cancer screening program. This article is protected by copyright. All rights reserved.

摘要

目的: 本研究旨在评估积极配合和随后结肠镜检查后的心理功能、生活质量和对筛查的遗憾,并评估随时间的变化。 方法: 这是一项前瞻性队列研究。2017年7月至 2018年11月期间转诊接受结肠镜检查的粪便免疫化学试验 (FIT) 阳性的 55-75 岁个体,被邀请在三个预定的时间点完成与心理困扰和健康相关生活质量相关的问卷调查: 结肠镜检查前、组织病理学结果通知后和 6 个月后。采用四份问卷: 心理后果问卷 (PCQ) 、 6 项癌症担忧量表 (CWS) 、决策后悔量表 (DRS) 、和 36 项的短形式 (SF-36)。 结果: 共纳入 1066 例合格个体中的 2151 例参与者。癌症患者在结肠镜检查结果通知后,心理功能障碍 (P = 0.01) 和癌症担忧 (P = 0.008) 显著增加,六个月后结肠镜检查前测量值下降。在非癌症组中,心理功能障碍和癌症担忧随时间显著下降 (P <0.05),但没有持续下降。六个月后,17% 没有癌症的参与者经历了高水平的癌症担忧 (cws ≥ 10)。然而,只有 5% 的人报告了对筛查参与的高度遗憾 (drs> 25)。在没有癌症的参与者中报告了良好的全球生活质量。 结论: 在荷兰肠癌筛查项目中检测假阳性的参与者在结肠镜检查后 6 个月仍存在一些心理困扰。本文受版权保护。保留所有权利。

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影响因子:2.69
发表时间:2020-01-18
DOI:10.1016/j.bbrc.2020.01.048
作者列表:["Li Y","Wang Z","Jin J","Zhu SX","He GQ","Li SH","Wang J","Cai Y"]

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影响因子:2.46
发表时间:2020-01-01
DOI:10.1097/COC.0000000000000609
作者列表:["Appelt AL","Andersen RF","Lindebjerg J","Jakobsen A"]

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