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人乳头瘤病毒疫苗预防宫颈癌的现实效果
Real-World Effectiveness of Human Papillomavirus Vaccination Against Cervical Cancer
From：J Natl Cancer Inst Date：2021-10-01
IF：13.5 类型：临床
Read：228 Author：Kjaer SK
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长春新碱-伊立替康联合或不联合替莫唑胺在复发或难治性横纹肌肉瘤儿童和成人中的随机II期试验：欧洲儿童软组织肉瘤研究组和儿童癌症创新疗法试验
Randomized Phase II Trial of Vincristine-Irinotecan With or Without Temozolomide, in Children and Adults With Relapsed or Refractory Rhabdomyosarcoma: A European Paediatric Soft tissue Sarcoma Study Group and Innovative Therapies for Children With Cancer Trial
From：J Clin Oncol Date：2021-09-20
IF：44.5 类型：临床
Read：380 Author：Defachelles AS
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PARP7负向调节肿瘤细胞I型干扰素反应，其抑制可触发抗肿瘤免疫
PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity
From：Cancer Cell Date：2021-09-13
IF：31.7 类型：基础
Read：238 Author：Gozgit JM
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一项评估非住院癌症手术后门诊病人症状电子监测的随机对照试验
A Randomized Controlled Trial Evaluating Electronic Outpatient Symptom Monitoring After Ambulatory Cancer Surgery
From：Ann Surg Date：2021-09-01
IF：12.9 类型：临床
Read：170 Author：Andrea L. Pusic
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TCR和CAR信号的比较分析为具有卓越抗原敏感性的CAR设计提供信息
Comparative analysis of TCR and CAR signaling informs CAR designs with superior antigen sensitivity
From：Sci Signal Date：2021-08-24
IF：8.1 类型：基础
Read：279 Author：Alexander I. Salter
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B细胞成熟抗原×CD3双特异性抗体Teclistamab治疗复发或难治性多发性骨髓瘤（MajesTEC-1）：一项多中心、开放标记、单臂、1期研究
Teclistamab, a B-cell maturation antigen × CD3 bispecific antibody, in patients with relapsed or refractory multiple myeloma (MajesTEC-1): a multicentre, open-label, single-arm, phase 1 study
From：Lancet Date：2021-08-21
IF：79.3 类型：临床
Read：160 Author：Usmani SZ
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通过循环肿瘤DNA的低深度全基因组测序阐明前列腺癌治疗期间的行为
Elucidating Prostate Cancer Behaviour During Treatment via Low-pass Whole-genome Sequencing of Circulating Tumour DNA
From：Eur Urol Date：2021-08-20
IF：20.1 类型：临床
Read：667 Author：Semini Sumanasuriya
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CIP2A与TopBP1相互作用并驱动基底样乳腺癌肿瘤发生
CIP2A interacts with TopBP1 and drives basal-like breast cancer tumorigenesis
From：Cancer Res Date：2021-08-15
IF：12.7 类型：基础
Read：321 Author：Anni Laine
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晚期胃癌和胃食管交界癌的生物标志物靶向治疗：一个新兴的模式
Biomarker-targeted therapies for advanced-stage gastric and gastro-oesophageal junction cancers: an emerging paradigm
From：NAT REV CLIN ONCOL Date：2021-08-15
IF：66.7 类型：综述
Read：589 Author：Nakamura Y
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NKG2D-CAR转导的自然杀伤细胞有效靶向多发性骨髓瘤
NKG2D-CAR-transduced natural killer cells efficiently target multiple myeloma
From：Blood Cancer J Date：2021-08-14
IF：11.0 类型：基础
Read：160 Author：Alejandra Leivas
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胰腺癌同源重组缺陷：系统综述和流行病学荟萃分析
Homologous Recombination Deficiency in Pancreatic Cancer: A Systematic Review and Prevalence Meta-Analysis
From：J Clin Oncol Date：2021-08-10
IF：44.5 类型：综述
Read：184 Author：Casolino R
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靶向骨转移微环境的新方法
Novel approaches to target the microenvironment of bone metastasis
From：Nat Rev Clin Oncol Date：2021-08-05
IF：66.6 类型：综述
Read：182 Author：Lorenz C. Hofbauer
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增殖性癌症持久细胞来不同程序的谱系
Cycling cancer persister cells arise from lineages with distinct programs
From：Nature Date：2021-08-01
IF：49.9 类型：基础
Read：188 Author：Oren Y
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CTLA-4反馈通路阻断后瘤内Treg细胞扩增
Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop
From：Cell Date：2021-07-22
IF：41.6 类型：基础
Read：438 Author：Marangoni F
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Tim-4+ 体腔驻留巨噬细胞损害CD8+ T细胞抗肿瘤免疫
Tim-4+ cavity-resident macrophages impair antitumor CD8+ T cell immunity
From：Cancer Cell Date：2021-07-12
IF：31.7 类型：基础
Read：311 Author：Chow A
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肠道微生物群特征与CTLA-4和PD-1联合阻断的毒性相关
Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade
From：Nat Med Date：2021-07-08
IF：53.4 类型：基础
Read：345 Author：Andrews MC
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NTRK 和 RET 融合靶向治疗小儿甲状腺癌产生肿瘤应答和放射性碘摄取
NTRK and RET fusion-directed therapy in pediatric thyroid cancer yields a tumor response and radioiodine uptake
From：J Clin Invest Date：2021-07-08
IF：14.8 类型：基础
Read：114 Author：Young Ah Lee
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液体活检在抗癌药物开发药理学审核中的应用
Applications of liquid biopsy in the Pharmacological Audit Trail for anticancer drug development
From：Nat Rev Clin Oncol Date：2021-07-01
IF：66.6 类型：综述
Read：237 Author：Pal A
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相分离驱动异常染色质成环和癌症发展
Phase separation drives aberrant chromatin looping and cancer development
From：Nature Date：2021-07-01
IF：49.9 类型：基础
Read：219 Author：Ahn JH
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ctDNA指导尿路上皮癌的辅助免疫治疗
ctDNA guiding adjuvant immunotherapy in urothelial carcinoma
From：Nature Date：2021-07-01
IF：49.9 类型：临床
Read：91 Author：Powles T
