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卡博替尼加阿特珠单抗与索拉非尼治疗晚期肝细胞癌的比较(COSMIC-312):随机3期研究的最终结果
Cabozantinib plus atezolizumab versus sorafenib for advanced hepatocellular carcinoma (COSMIC-312): final results of a randomised phase 3 study
From:Lancet Gastroenterol Hepatol Date:2024-04-01
IF:35.6 类型:临床
Read:32 Author:Thomas Yau
一线使用德瓦鲁单抗治疗PD-L1阳性、PS2、晚期非小细胞肺癌(NSCLC)患者:多中心、单臂、II期试验SAKK 19/17的主要分析
First-line durvalumab in patients with PD-L1 positive, advanced non-small cell lung cancer (NSCLC) with a performance status of 2 (PS2). Primary analysis of the multicenter, single-arm phase II trial SAKK 19/17
From:Eur J Cancer Date:2024-03-01
IF:8.4 类型:临床
Read:21 Author:Michael Mark
ES-SCLC一线治疗的最新进展和未来策略
Recent advances and future strategies in first-line treatment of ES-SCLC
From:Eur J Cancer Date:2024-03-01
IF:8.4 类型:综述
Read:17 Author:Igor Gomez-Randulfe
ATRi(Ceralasertib)通过调节肿瘤微环境增强肿瘤检查点免疫治疗
The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironment
From:Nat Commun Date:2024-02-24
IF:16.6 类型:基础
Read:7 Author:Elizabeth L Hardaker
在肾透明细胞癌中,靶向MYC通过上调HILPDA诱导脂滴积聚
Targeting MYC induces lipid droplet accumulation by upregulation of HILPDA in clear cell renal cell carcinoma
From:PNAS Date:2024-02-13
IF:11.1 类型:基础
Read:19 Author:Lourdes Sainero-Alcolado
一线纳武单抗、伊匹单抗联合化疗治疗转移性非小细胞肺癌的四年临床更新和治疗转换调整后的结局:CheckMate 9LA随机试验
Four- year clinical update and treatment switching-adjusted outcomes with first-line nivolumab plus ipilimumab with chemotherapy for metastatic non- small cell lung cancer in the CheckMate 9LA randomized trial
From:J Immunother Cancer Date:2024-02-12
IF:10.8 类型:临床
Read:9 Author:David P Carbone
乐伐替尼的分子相互作用模式可抑制野生型或激酶突变的FGFR2驱动的胆管癌
The molecular interaction pattern of lenvatinib enables inhibition of wild-type or kinase-mutated FGFR2-driven cholangiocarcinoma
From:Nat Commun Date:2024-02-12
IF:16.6 类型:基础
Read:5 Author:Stephan Spahn
用于胰腺癌细胞球动态培养的明胶水凝胶粘弹性增韧技术
Viscoelastic stiffening of gelatin hydrogels for dynamic culture of pancreatic cancer spheroids
From:Acta Biomater Date:2024-02-12
IF:9.7 类型:基础
Read:5 Author:Han D Nguyen
接受完全新辅助治疗的直肠腺癌患者器官保留的长期结果:随机II期OPRA试验
Long-Term Results of Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy: The Randomized Phase II OPRA Trial
From:J Clin Oncol Date:2024-02-10
IF:45.3 类型:临床
Read:6 Author:Floris S Verheij
CAR-T细胞制造:主要工艺参数和下一代策略
CAR-T cell manufacturing: Major process parameters and next-generation strategies
From:J Exp Med Date:2024-02-05
IF:15.2 类型:综述
Read:38 Author:Melanie Ayala Ceja
使用Tumor-Naïve下一代测序面板循环肿瘤DNA序列分析,检测最小残留疾病并预测卵巢癌的预后
Serial Circulating Tumor DNA Analysis with a Tumor-Naïve Next-Generation Sequencing Panel Detects Minimal Residual Disease and Predicts Outcome in Ovarian Cancer
From:Cancer Res Date:2024-02-01
IF:11.2 类型:基础
Read:8 Author:Jinho Heo
胆管癌的分子病理学:可操作的基因靶点及其与辅助和新辅助治疗、分期、随访和最小残留疾病确定的相关性的综述
Molecular pathology for cholangiocarcinoma: a review of actionable genetic targets and their relevance to adjuvant & neoadjuvant therapy, staging, follow-up, and determination of minimal residual disease
From:Hepatobiliary Surg Nutr Date:2024-02-01
IF:8.0 类型:综述
Read:10 Author:Emilie A K Warren
SKYSCRAPER-02:替瑞利尤单抗加阿替利珠单抗联合化疗治疗未经治疗的广泛期小细胞肺癌
SKYSCRAPER-02: Tiragolumab in Combination With Atezolizumab Plus Chemotherapy in Untreated Extensive-Stage Small-Cell Lung Cancer
From:J Clin Oncol Date:2024-01-20
IF:45.3 类型:临床
Read:4 Author:Charles M Rudin
洛普替尼在ROS1融合阳性非小细胞肺癌中的应用
Repotrectinib in ROS1 Fusion–Positive Non–Small-Cell Lung Cancer
From:N Engl J Med Date:2024-01-11
IF:158.4 类型:临床
Read:21 Author:Alexander Drilon
腹腔热灌注化疗对接受细胞减灭术的胃癌腹膜转移患者的影响:III期GASTRIPEC-I试验
Effect of Hyperthermic Intraperitoneal Chemotherapy on Cytoreductive Surgery in Gastric Cancer With Synchronous Peritoneal Metastases: The Phase III GASTRIPEC-I Trial
From:J Clin Oncol Date:2024-01-10
IF:45.3 类型:临床
Read:5 Author:Beate Rau
二甲双胍联合靶向治疗对人乳腺癌细胞系的增强作用
Enhancement of targeted therapy in combination with metformin on human breast cancer cell lines
From:Cell Commun Signal Date:2024-01-02
IF:8.4 类型:基础
Read:15 Author:Ghazal Mahmoudi
根据临床反应等级评估新辅助治疗对直肠癌患者器官保留和生存的影响:OPRA随机临床试验的二次分析
Organ Preservation and Survival by Clinical Response Grade in Patients With Rectal Cancer Treated With Total Neoadjuvant Therapy: A Secondary Analysis of the OPRA Randomized Clinical Trial
From:JAMA Netw Open Date:2024-01-02
IF:13.7 类型:临床
Read:6 Author:Hannah M Thompson
Divarasib联合西妥昔单抗治疗KRAS G12C阳性结直肠癌:1b期试验
Divarasib plus cetuximab in KRAS G12C-positive colorectal cancer: a phase 1b trial
From:Nat Med Date:2024-01-01
IF:82.8 类型:临床
Read:5 Author:Jayesh Desai
脂肪肉瘤中的MDM2-p53:需要新的作用机制的靶向治疗
MDM2-p53 in liposarcoma: The need for targeted therapies with novel mechanisms of action
From:Cancer Treat Rev Date:2024-01-01
IF:11.7 类型:综述
Read:5 Author:Neeta Somaiah
DNA疫苗(pTVG-HP)联合纳武单抗治疗去势敏感性非转移性(M0)前列腺癌患者的2期试验
Phase 2 trial of a DNA vaccine (pTVG-HP) and nivolumab in patients with castration-sensitive non-metastatic (M0) prostate cancer
From:J Immunother Cancer Date:2023-12-14
IF:10.8 类型:临床
Read:11 Author:Douglas G McNeel
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