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Salt-and-Pepper Noise Sign on Fat-Fraction Maps by Chemical-Shift-Encoded MRI: A Useful Sign to Differentiate Bone Islands From Osteoblastic Metastases-A Preliminary Study.

化学移位编码MRI在脂肪分数图上的盐和胡椒噪声标志: 鉴别骨岛和成骨细胞转移的有用标志-初步研究。

  • 影响因子:2.91
  • DOI:10.2214/AJR.19.22177
  • 作者列表:"Jeon SW","Kwack KS","Yun JS","Gho SM","Park S
  • 发表时间:2020-05-01
Abstract

:OBJECTIVE. The objective of our study was to assess the diagnostic utility of the "salt-and-pepper noise" sign on fat-fraction maps by chemical-shift-encoded MRI (CSE-MRI) compared with the halo sign on fat-suppressed T2-weighted imaging and mean attenuation on CT for differentiating bone islands from osteoblastic metastases. MATERIALS AND METHODS. Twenty-nine patients with 43 sclerotic vertebral bone marrow lesions (26 osteoblastic metastases, 17 bone islands) were included retrospectively. All patients underwent CT and MRI, including a CSE-MRI sequence on a 1.5-T MRI system, from November 2016 to January 2019. The salt-and-pepper noise sign was defined as the speckled appearance of white and black pixels that is similar to the appearance of background air on a fat-fraction map. ROC curves were analyzed to compare the diagnostic performance of the salt-and-pepper noise sign, halo sign, and mean CT attenuation between the two groups. RESULTS. The salt-and-pepper noise sign was significantly associated with bone islands (p < 0.001). The sensitivity, specificity, and accuracy for discriminating bone islands from osteoblastic metastases were 92.31-96.15%, 100%, and 95.35-97.67% for the salt-and-pepper noise sign; 88.46-92.31%, 88.24-94.12%, and 90.70% for the halo sign; and 96.15%, 94.12-100%, and 95.35-97.67% for mean CT attenuation, respectively. There was no statistically significant difference of diagnostic performances among the imaging characteristics for differentiating between bone islands and osteoblastic metastases (p > 0.05). Interobserver agreement for the salt-and-pepper noise sign, halo sign, and mean CT attenuation was almost perfect (κ ≥ 0.953, κ = 0.905, and ICC = 0.966, respectively). CONCLUSION. The salt-and-pepper noise sign is present in bone islands on fat-fraction maps by CSE-MRI and can aid in differentiating bone islands from osteoblastic metastases.

摘要

: 目的。我们研究的目的是通过化学位移编码MRI (CSE-MRI) 评估脂肪分数图上 “椒盐噪声” 标志的诊断效用与脂肪抑制T2-weighted成像上的晕征和CT上的平均衰减比较,用于鉴别骨岛和成骨转移瘤。材料和方法。回顾性纳入 29 例 43 个椎体硬化骨髓病变 (26 个成骨转移瘤,17 个骨岛)。所有pa t ien t s underwen t C T和MRI,包括 1.5-T MRI sys t em上的CSE-MRI序列,自 2016 年 11 月t o 2019 年 1 月。盐和胡椒噪声标志被定义为白色和黑色像素的斑点外观,类似于脂肪分数图上背景air的外观。分析ROC曲线,比较两组椒盐噪声征、晕征和平均CT衰减的诊断性能。结果。椒盐噪声征与骨岛显著相关 (p <0.001)。区分骨岛与成骨转移瘤的敏感性、特异性和准确性为椒盐噪声征的 92.31-96.15% 、 100% 和 95.35-97.67%; 88.46-92.31%,晕征分别为 88.24-94.12% 和 90.70%; 平均CT衰减分别为 96.15% 、 94.12-100% 和 95.35-97.67%。骨岛与骨转移瘤的影像学特征鉴别诊断差异无统计学意义 (p> 0.05)。盐和胡椒噪声征、晕征和平均CT衰减的观察者间一致性几乎完全 (κ ≥ 0.953,κ = 0.905,ICC = 0.966)。结论。通过CSE-MRI在脂肪分数图上的骨岛中存在椒盐噪声征,可帮助鉴别骨岛和成骨细胞转移。

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影响因子:1.41
发表时间:2020-03-01
DOI:10.1177/1078155219842277
作者列表:["Gyori DJ","Bullington SM","Crawford BS","Vernon VP"]

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影响因子:2.83
发表时间:2020-01-01
DOI:10.1007/s00520-019-04843-9
作者列表:["Dohzono S","Sasaoka R","Takamatsu K","Hoshino M","Nakamura H"]

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骨肿瘤方向

骨肿瘤是发生于骨骼或其附属组织的肿瘤。有良性,恶性之分,良性骨肿瘤易根治,预后良好,恶性骨肿瘤发展迅速,预后不佳,死亡率高。

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