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Frequency of Large Intrafractional Target Motions During Spine Stereotactic Body Radiation Therapy.

脊柱立体定向体部放射治疗过程中大关节内靶运动的频率。

  • 影响因子:2.28
  • DOI:10.1016/j.prro.2019.08.006
  • 作者列表:"Wu J","Wu J","Ballangrud Å","Mechalakos J","Yamada J","Lovelock DM
  • 发表时间:2020-01-01
Abstract

:Spine stereotactic body radiation therapy frequently involves the delivery of high doses to targets in proximity to the spinal cord; thus, the radiation must be delivered with great spatial accuracy. Monitoring for large shifts in target and cord position that might occur during dose delivery is a challenge for clinics equipped with a conventional C-arm Linac. Treatment must be halted, then imaging and registration must be done to determine whether a significant shift has occurred. In this retrospective study of 1019 spine SBRT treatments, we investigated the number of target shifts >2 mm in any direction that occurred in carefully immobilized patients. Orthogonal kV images were acquired 3 to 5 times during each session using in an in-room imaging system. Although the likelihood of large intrafractional shifts was found to be very low, they did occur in 6 treatment sessions. Intrafractional monitoring was found to be an important safety component of treatment delivery.

摘要

: 脊柱立体定向体部放射治疗经常涉及向脊髓附近的目标输送高剂量; 因此,必须以很高的空间精度输送辐射。对于配备常规c型臂直线加速器的诊所来说,监测剂量输送过程中可能发生的目标和脐带位置的大变化是一个挑战。必须停止治疗,然后必须进行成像和配准,以确定是否发生了重大转变。在这项 1019 例脊柱SBRT治疗的回顾性研究中,我们调查了在仔细固定的患者中发生的任何方向的目标偏移> 2毫米的数量。使用室内成像系统,每次采集正交kV图像 3 ~ 5 次。虽然发现大的内转移的可能性非常低,但它们确实发生在 6 次治疗中。发现牵拉式监测是治疗输送的重要安全组成部分。

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作者列表:["Tran S","Puric E","Walser M","Poel R","Datta NR","Heuberger J","Pica A","Marder D","Lomax N","Bolsi A","Morach P","Bachtiary B","Seddon BM","Schneider R","Bodis S","Weber DC"]

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DOI:10.1177/1078155219842277
作者列表:["Gyori DJ","Bullington SM","Crawford BS","Vernon VP"]

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骨肿瘤是发生于骨骼或其附属组织的肿瘤。有良性,恶性之分,良性骨肿瘤易根治,预后良好,恶性骨肿瘤发展迅速,预后不佳,死亡率高。

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