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Case report of periorbital metastasis from rectal cancer.

直肠癌眶周转移病例报告。

  • 影响因子:1.95
  • DOI:10.1097/MD.0000000000018479
  • 作者列表:"Paik JH","Shin HJ","Lee HS","Han HS","Ryu CG","Hwang DY
  • 发表时间:2020-01-01
Abstract

INTRODUCTION:Periorbital metastasis of colorectal cancer is rare. Therefore, herein, we report a patient with rectal cancer who presented with periorbital metastasis without any systemic metastasis. PATIENT CONCERNS:The patient was a 57-year-old man who had a painless nodule on his left eyelid. DIAGNOSIS:The patient presented with loose and frequent stools and was diagnosed with rectal adenocarcinoma via colonoscopic biopsy at the local clinic. Curative resection (low anterior resection with temporary ileostomy formation) was performed 4 weeks after completing chemoradiotherapy. The final TNM stage was yp stage T2N0M0. Eight months after the diagnosis of rectal cancer, a protruding lesion was noticed on the patient's left eyelid. Histologic evaluation of the nodule revealed metastatic adenocarcinoma of rectal cancer. INTERVENTIONS:The patient received neoadjuvant chemoradiotherapy and curative resection for rectal cancer. After excision of the periorbital nodule, he received 5 cycles of chemotherapy. OUTCOMES:The patient underwent regular follow-up because he was not able to endure chemotherapy; no recurrence has been observed 21 months after the diagnosis of rectal cancer. Histologic examination revealed metastatic adenocarcinoma of rectal cancer on the patient's left eyelid. However, consecutive imaging studies revealed no other metastatic lesions. Finally, the patient was diagnosed with a solitary periorbital metastasis of rectal cancer. CONCLUSION:This case report helps in understanding the course of progression from rectal cancer to periorbital metastasis.

摘要

导读: 结直肠癌眶周转移少见。因此,在此,我们报告了 1 例直肠癌患者,其表现为眶周转移,无任何全身转移。 患者顾虑: 患者男,57 岁,左眼睑有无痛性结节。 诊断: 患者表现为稀便和频繁,在当地诊所经结肠镜活检确诊为直肠腺癌。完成放化疗后 4 周进行根治性切除 (低位前切除术加临时回肠造口术)。最终TNM分期为yp分期T2N0M0。诊断为直肠癌 8 个月后,注意到患者的左眼睑有一个突出的病变。结节的组织学评价发现直肠癌的转移性腺癌。 干预措施: 患者接受新辅助放化疗和直肠癌根治性切除术。眶周结节切除术后,他接受了 5 个周期的化疗。 结果: 患者接受了定期随访,因为他不能忍受化疗; 直肠癌诊断后 21 个月未观察到复发。组织学检查发现患者左侧眼睑出现直肠癌转移性腺癌。然而,连续的影像学检查未发现其他转移病灶。最后,患者被诊断为孤立的直肠癌眶周转移。 结论: 本病例报告有助于了解从直肠癌进展到眶周转移的过程。

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骨肿瘤是发生于骨骼或其附属组织的肿瘤。有良性,恶性之分,良性骨肿瘤易根治,预后良好,恶性骨肿瘤发展迅速,预后不佳,死亡率高。

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