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Retinal ischemia due to extramedullary plasmacytomas of the orbit.
眼眶髓外浆细胞瘤引起的视网膜缺血。
- 影响因子:1.63
- DOI:10.1016/j.jocn.2020.01.052
- 作者列表:"Lasocki A","Furphy EJ","Westerman DA","Harrison S
- 发表时间:2020-02-01
Abstract
:Visual disturbance is a common complaint in patients with multiple myeloma, both at diagnosis and later in their course, and has a broad differential. Here, we report a novel cause of visual disturbance, namely retinal ischemia due to extramedullary plasmacytomas of the orbit. A 69 year-old male patient with known multiple myeloma presented with reduced vision in his left eye. The patient had been initially diagnosed with IgG myeloma 9 months earlier and multiples lines of medical therapy had been unsuccessful. Ophthalmology review was organised and fundoscopic examination showed evidence of retinal ischemia. Computed tomography of the orbits demonstrated multiple enhancing masses within both orbits, consistent with extramedullary plasmacytomas. The presence of retinal ischemia was thus attributed to mass effect on the orbital vessels. Extramedullary plasmacytomas within the orbit are a rare manifestation of multiple myeloma, but important to consider as a possible cause of visual disturbance.
摘要
: 视觉障碍是多发性骨髓瘤患者的常见主诉,无论是在诊断时还是后期,都有广泛的鉴别。在此,我们报道了视觉障碍的一个新原因,即眼眶髓外浆细胞瘤引起的视网膜缺血。一名 69 岁已知多发性骨髓瘤男性患者,左眼视力下降。患者在 9 个月前被初步诊断为IgG骨髓瘤,多行药物治疗不成功。组织了眼科检查,眼底镜检查显示视网膜缺血的证据。眼眶计算机断层扫描显示两个眼眶内有多个增强肿块,与髓外浆细胞瘤一致。因此,视网膜缺血的存在归因于眼眶血管上的肿块效应。眼眶内的髓外浆细胞瘤是多发性骨髓瘤的罕见表现,但重要的是要考虑为视觉障碍的可能原因。
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骨肿瘤是发生于骨骼或其附属组织的肿瘤。有良性,恶性之分,良性骨肿瘤易根治,预后良好,恶性骨肿瘤发展迅速,预后不佳,死亡率高。