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Carbon dots derived from lychee waste: Application for Fe3+ ions sensing in real water and multicolor cell imaging of skin melanoma cells.

来源于荔枝废物的碳点: 应用Fe3 + 离子传感在真实水和皮肤黑色素瘤细胞的多色细胞成像。

  • 影响因子:5.07
  • DOI:10.1016/j.msec.2019.110429
  • 作者列表:"Sahoo NK","Jana GC","Aktara MN","Das S","Nayim S","Patra A","Bhattacharjee P","Bhadra K","Hossain M
  • 发表时间:2020-03-01
Abstract

:Exploit of biomass as an inexhaustible resource has accepted much more curiosity to the present research world. Herein, a simple, one-step solvothermal action has been used to synthesize an ascendable amount of fluorescent carbon dots (CDs) with an average size of~3.13 nm, from Low-reasonable and green source lychee waste. The excitation/emission maxima of CDs have 365/443 nm with high quantum yield (23.5%). The present ingredient predominantly contained carboxylic acid and hydroxyl group that acted as a passive agent for stabilizing the CDs. The structural and optical properties were evaluated through HRTEM, FTIR, UV-vis, zeta potential, XPS, fluorescence, and fluorescence lifetime experiments. We investigated the manoeuvre of our synthesized CDs as a probe for detection of Fe3+ ions in water bodies; This sensing approach showed impressive selectivity and sensitivity towards Fe3+ions with LOD 23.6 nM. The sensing mechanism took place through static quenching which was entrenched through fluorescence lifetime measurements. Fe3+ ions detection was basically carried out with efficacy in real water. For its lofty Photo-stability, low cytotoxicity and cell viability the probe were substantially applied for bio-imaging experiment i.e. intracellular multi-color cell imaging in skin melanoma cells (A375 cells) with and without Fe3+ ions exemplifying its real applications in living cells.

摘要

: 生物质作为一种取之不尽、用之不竭的资源,对目前的研究世界已经接受了更多的好奇心。在此,使用简单的一步溶剂热作用合成了平均尺寸为 ~ 3.13 nm的可增加数量的荧光碳点 (CDs),从低-合理和绿色来源荔枝废物。CDs的激发/发射极大值为 365/443 nm,量子产率高 (23.5%)。本成分主要含有羧酸和羟基,作为稳定CDs的被动剂。通过HRTEM、FTIR、UV-vis、zeta电位、XPS、荧光和荧光寿命实验评价了其结构和光学性能。我们研究了我们合成的CDs作为探测水体中Fe3 + 离子的探针的操作; 这种传感方法对LOD为 23.6 nm的Fe3 + 离子表现出令人印象深刻的选择性和灵敏度。传感机制是通过静态猝灭发生的,通过荧光寿命测量根深蒂固。在实际水中基本上进行了Fe3 + 离子的有效检测。由于其高度的光稳定性、低细胞毒性和细胞活力,该探针被大量应用于生物成像实验,即含和不含Fe3 + 离子的皮肤黑色素瘤细胞 (A375 细胞) 的细胞内多色细胞成像举例说明其在活细胞中的真正应用。

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影响因子:2.93
发表时间:2020-01-01
DOI:10.1016/j.jaad.2019.04.067
作者列表:["Pham CT","Juhasz M","Sung CT","Mesinkovska NA"]

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影响因子:0.96
发表时间:2020-01-01
DOI:10.1097/DAD.0000000000001459
作者列表:["Lang UE","Love NR","Cheung C","McCalmont TH","Kim J"]

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皮肤肿瘤方向

皮肤肿瘤是发生在皮肤的细胞增生性疾病,是一种常见病。发生于皮内或皮下组织的新生物,种类很多,临床上分良性肿瘤和恶性肿瘤。恶性肿瘤可以不断增殖,引起转移,威胁生命,称为皮肤癌。

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