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Melanoma Characteristics in Patients with a History of UV Tanning Bed Usage.

有紫外线日光浴床使用史患者的黑色素瘤特征。

  • 影响因子:1.59
  • DOI:10.1177/0003489420904744
  • 作者列表:"Truong K","Milhem M","Pagedar NA
  • 发表时间:2020-07-01
Abstract

OBJECTIVE:The purpose of this study was to evaluate the effect of tanning bed use on the behavior of subsequent melanomas. METHODS:Cases of invasive cutaneous melanoma who completed a baseline questionnaire within 1 year of biopsy were ascertained using an institutional registry. Patients were categorized into one of two groups: (1) no history of UV tanning bed usage or (2) any history of tanning bed usage. Data analysis looked for group differences on the following variables: TNM staging, mitotic rate, family history of melanoma, and basic demographic variables. RESULTS:Among 141 cases, a higher percentage of women (48.28%) reported tanning bed usage compared to men (26.51%, P < .01). Additionally, the average age at biopsy for people who reported tanning bed usage was significantly lower compared to those who had not reported using a tanning bed. There was no significant difference in stage at presentation (P = .56). Those with tanning bed usage presented significantly less often with melanoma of unknown primary (MUP). After controlling for the effects of gender and nodal status, tanning bed usage was not a significant independent predictor of 5 year overall survival. CONCLUSIONS:If we remove the subject with MUP on the basis that more of these are mucosal in origin, lower TNM stage at presentation are found in patients with no tanning bed melanoma compared to those with history of tanning bed usage. In addition, tanning bed patients are younger and more likely female but with an equivalent mortality rate. LEVEL OF EVIDENCE:Case Series.

摘要

目的: 本研究的目的是评估使用日光浴床对后续黑色素瘤行为的影响。 方法: 使用机构登记处确定在活检 1 年内完成基线问卷的侵袭性皮肤黑色素瘤病例。将患者分为两组 :( 1) 无UV日光浴床使用史或 (2) 任何日光浴床使用史。数据分析寻找以下变量的组间差异: TNM分期、核分裂率、黑色素瘤家族史和基本人口学变量。 结果: 在 141 例病例中,女性 (48.28%) 报告使用日光浴床的比例高于男性 (26.51%,p <.01)。此外,报告使用日光浴床的人的活检平均年龄明显低于未报告使用日光浴床的人。就诊时分期无显著差异 (p =.56)。使用日光浴床的患者明显较少出现未知原发性黑色素瘤 (MUP)。在控制了性别和淋巴结状态的影响后,日光浴床的使用不是 5 年总生存率的显著独立预测因子。 结论: 如果我们在其中更多是粘膜起源的基础上用MUP去除受试者,与有日光浴床使用史的患者相比,在无日光浴床黑色素瘤的患者中发现了较低的TNM分期。此外,日光浴床患者更年轻,更可能是女性,但具有相当的死亡率。 证据水平: 病例系列。

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影响因子:2.93
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DOI:10.1016/j.jaad.2019.04.067
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影响因子:0.96
发表时间:2020-01-01
DOI:10.1097/DAD.0000000000001459
作者列表:["Lang UE","Love NR","Cheung C","McCalmont TH","Kim J"]

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皮肤肿瘤方向

皮肤肿瘤是发生在皮肤的细胞增生性疾病,是一种常见病。发生于皮内或皮下组织的新生物,种类很多,临床上分良性肿瘤和恶性肿瘤。恶性肿瘤可以不断增殖,引起转移,威胁生命,称为皮肤癌。

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