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Risk of Intracranial Extension of Craniofacial Dermoid Cysts.

颅面皮样囊肿颅内扩展的风险。

  • 影响因子:1.74
  • DOI:10.1097/PRS.0000000000006655
  • 作者列表:"Overland J","Hall C","Holmes A","Burge J
  • 发表时间:2020-04-01
Abstract

BACKGROUND:Dermoid cysts are benign lesions lined by keratinizing squamous epithelium that also contain epidermal adnexa (hair follicles, hair shafts, sebaceous glands, and both apocrine and eccrine sweat glands) and mesodermal derivatives (smooth muscle fibers, vascular stroma, nerves, and collagen fibers). Craniofacial dermoid cysts represent approximately 7 percent of all dermoids and have an incidence ranging between 0.03 and 0.14 percent. METHODS:The authors conducted a single-center, consecutive, nonrandomized comparative case series over a 20-year period of all patients treated surgically for craniofacial dermoid at the Royal Children's Hospital in Melbourne, Australia. Six hundred forty-seven patients had craniofacial dermoids and adequate information to be included in the study. The authors also conducted a thorough review of the literature using the MEDLINE and Embase databases. RESULTS:Six hundred forty-seven patients amounted to 655 lesions in our case series. The age at surgery ranged from 2 months to 18 years, with an average age of 25.65 months. The depth of the lesions was stratified using a classification system, and the risk of intracranial extension was assessed using these data. Midline nasal lesions are established as high risk by other studies, but frontal, temporal, and occipital lesions were found to be as risky if not more risky for intracranial extension. CONCLUSIONS:Several classification systems for craniofacial dermoid cysts have used both broader anatomical locations and physical characteristics to group these lesions and identify those warranting preoperative imaging. The authors propose a system using more specific classification of anatomical location to assist in the prompt identification of high-risk lesions and facilitate sound preoperative planning. CLINICAL QUESTION/LEVEL OF EVIDENCE:Therapeutic, V.

摘要

背景: 皮样囊肿是由角化鳞状上皮排列的良性病变,也含有表皮附件 (毛囊、毛干、皮脂腺以及大汗腺和小汗腺) 和中胚层衍生物 (平滑肌纤维、血管间质、神经和胶原纤维)。颅面皮样囊肿约占所有皮样的 7%,发病率在 0.03 至 0.14% 之间。 方法: 作者在墨尔本皇家儿童医院对所有手术治疗的颅面皮样瘤患者进行了 20 年的单中心、连续、非随机对照病例系列研究。澳大利亚。647 例患者有颅面皮样变,有足够的信息纳入研究。作者还使用MEDLINE和Embase数据库对文献进行了彻底的综述。 结果: 在我们的病例系列中,647 例患者占 655 个病灶。手术时年龄 2 个月 ~ 18 岁,平均年龄 2 5.65 个月。使用分类系统对病变深度进行分层,并使用这些数据评估颅内扩展的风险。其他研究将中线鼻病变确定为高风险,但发现额部、颞部和枕部病变对颅内扩展的风险较大,但风险较大。 结论: 颅面皮样囊肿的几种分类系统使用了更广泛的解剖位置和物理特征来对这些病变进行分组,并确定那些需要术前成像的病变。作者提出了一种使用更具体的解剖位置分类的系统,以协助及时识别高危病变,并促进合理的术前规划。 临床问题/证据水平: 治疗性,V.

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皮肤肿瘤方向

皮肤肿瘤是发生在皮肤的细胞增生性疾病,是一种常见病。发生于皮内或皮下组织的新生物,种类很多,临床上分良性肿瘤和恶性肿瘤。恶性肿瘤可以不断增殖,引起转移,威胁生命,称为皮肤癌。

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