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Multiple Epidermolytic Acanthomas: Rare Vulval Lesions Which May be Mistaken for Viral Warts.

多发性表皮松解性痤疮: 罕见的外阴病变,可能被误认为是病毒性疣。

  • 影响因子:1.60
  • DOI:10.1097/PGP.0000000000000570
  • 作者列表:"Irwin S","Karim A","McHenry P","Hutchinson S","Miller K","Jamison J","Houghton J","McCluggage WG
  • 发表时间:2020-01-01
Abstract

:Epidermolytic acanthoma is a rare benign lesion that most often presents as a solitary or multiple small papular lesions on the trunk, face, limbs or external male genitalia. Only a small number of cases have been reported occurring on the vulva and clinically and histologically they may mimic and be misdiagnosed as viral warts. We report 2 cases of multiple epidermolytic acanthomas localized to the vulva. Molecular tests (in situ hybridization and polymerase chain reaction) showed no evidence of human papillomavirus infection and p16 staining was negative. We stress the need for pathologists to consider epidermolytic acanthoma in the differential diagnosis of multiple vulval lesions resembling viral warts.

摘要

: 表皮松解性棘皮瘤是一种罕见的良性病变,最常表现为躯干、面部、四肢或男性外生殖器的单发或多发小丘疹性病变。只有少数病例报道发生在外阴,临床和组织学上可模拟并误诊为病毒疣。我们报告 2 例局限于外阴的多发性表皮松解性骨痛。分子检测 (原位杂交和聚合酶链反应) 没有人乳头瘤病毒感染的证据,p16 染色阴性。我们强调病理学家需要考虑表皮松解性棘皮瘤在类似病毒疣的多发性外阴病变的鉴别诊断疾病。

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皮肤肿瘤方向

皮肤肿瘤是发生在皮肤的细胞增生性疾病,是一种常见病。发生于皮内或皮下组织的新生物,种类很多,临床上分良性肿瘤和恶性肿瘤。恶性肿瘤可以不断增殖,引起转移,威胁生命,称为皮肤癌。

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