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Transungual Excision of Glomus Tumors: A Treatment and Quality of Life Study.

经脐切除血管球瘤: 治疗和生活质量研究。

  • 影响因子:1.25
  • DOI:10.1097/DSS.0000000000002006
  • 作者列表:"Reinders EFH","Klaassen KMG","Pasch MC
  • 发表时间:2020-01-01
Abstract

BACKGROUND:Glomus tumors are rare benign painful tumors, frequently found in the subungual region. Complete surgical excision is essential for relief of symptoms. The main postoperative complications are tumor recurrence and nail dystrophy. OBJECTIVE:To evaluate the long-term outcome and the impact on quality of life (QoL) of glomus tumors after a transungual approach. MATERIALS AND METHODS:A retrospective cohort study was conducted. Twenty-six patients underwent transungual excision of subungual glomus tumors. A self-administered questionnaire was sent to evaluate the postoperative outcome. Glomus tumor-related QoL was investigated using modified nail psoriasis (NPQ10) and onychomycosis questionnaires. RESULTS:A response rate of 85% was achieved. After a mean follow-up of 63 months after transungual excision of the tumor, the mean Numeric Pain Rating Score had improved from 7.9 (±SD 1.8) preoperatively, to 0.8 (±SD 1.9) (p < .000). Quality of life improved significantly: the mean NPQ10-score improved from 5.5 (±SD 3.4) to 0.64 (±SD 2.1) (p < .000). Nail-related sequelae were not reported in any of the patients. CONCLUSION:Our study showed that glomus tumors cause impairment on QoL, mostly due to severe pain. Surgical excision with the transungual approach is an effective treatment, without permanent damage to the nail unit that gives relief of pain and improves QoL.

摘要

背景: 血管球瘤是一种罕见的良性疼痛性肿瘤,好发于甲下区域。完整的手术切除对缓解症状至关重要。术后主要并发症为肿瘤复发和甲营养不良。 目的: 评价经甲途径治疗血管球瘤的远期疗效及其对患者生活质量的影响。 材料与方法: 采用回顾性队列研究。26 例患者接受甲下血管球瘤经甲切除。发送自填问卷以评价术后结果。使用改良指甲银屑病 (NPQ10) 和甲真菌病问卷调查血管球肿瘤相关QoL。 结果: 有效率为 85%。经十二指肠切除术后平均随访 63 个月,平均数字疼痛评分从术前的 7.9 (± SD 1.8) 提高到 0.8 (± SD 1.9) (p <.000)。生活质量显著改善: 平均NPQ10-score从 5.5 (± SD 3.4) 改善至 0.64 (± SD 2.1) (p <.000)。任何患者均未报告指甲相关后遗症。 结论: 我们的研究表明,血管球瘤导致QoL受损,主要是由于严重的疼痛。经甲入路手术切除是一种有效的治疗方法,对指甲单位无永久性损伤,可缓解疼痛,提高QoL。

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皮肤肿瘤方向

皮肤肿瘤是发生在皮肤的细胞增生性疾病,是一种常见病。发生于皮内或皮下组织的新生物,种类很多,临床上分良性肿瘤和恶性肿瘤。恶性肿瘤可以不断增殖,引起转移,威胁生命,称为皮肤癌。

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