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Non-HIV talaromycosis: Radiological and clinical analysis.

非HIV距骨真菌病: 放射学和临床分析。

  • 影响因子:1.95
  • DOI:10.1097/MD.0000000000019185
  • 作者列表:"Li X","Hu W","Wan Q","Lei Q","Sun C","Hou Z","Shrestha N
  • 发表时间:2020-03-01
Abstract

:To investigate the characteristics of spiral computed tomography (CT), positron emission tomography-computed tomography (PET/CT) and clinical manifestations of talaromycosis to improve the diagnostic level and deepen its recognition in radiology.Radiological, clinical, and pathological manifestations of 15 patients of non-HIV talaromycosis confirmed by bronchofiberscope lung biopsy and/or abscess puncture fluid culture and/or blood culture and/or sputum culture were analyzed retrospectively. All patients underwent chest CT, among them, six had a brain MRI, and six had a PET/CT scan before treatment.On plain CT scan, there were multiple patches and massive consolidation in 6 patients, multiple patchy consolidations and patchy ground-glass opacities in 3 patients, solitary or multiple nodules and masses in 3 patients, multiple cavities and small nodules in 3 patients. Multiple lymphadenectasis appeared in bilateral hila, mediastinum, and neck in 10 patients. In contrast CT scan, the parenchyma of the lesions had a slight enhancement in 10 patients, moderate enhancement in 3 patients, obvious enhancement in 2 patients. Seven cases had bone destruction and hyperplasia, cranial involvement in 1 patient and liver involvement in 3 patients, respectively. On PET/CT, five patients showed elevated standard uptake value (SUV).The radiological manifestations of non-HIV talaromycosis show multiple consolidations, ground-glass opacities, multiple nodules or masses in bilateral lungs, deep-seated enlarged lymph nodes and bone destruction in multiple systems. The final diagnosis should be based on the culture of talaromycosis.

摘要

: 探讨螺旋计算机断层扫描 (CT) 、正电子发射断层扫描-计算机断层扫描 (PET/CT) 的特点和临床表现,以提高诊断水平,加深对其在放射学的认识。放射学,临床,回顾性分析经纤维支气管镜肺活检和 (或) 脓肿穿刺液培养和 (或) 血培养和 (或) 痰培养证实的 15 例非HIV距骨真菌病患者的病理表现。所有患者均接受胸部CT检查,其中 6 例在治疗前进行了脑部MRI检查,6 例在治疗前进行了PET/CT扫描。CT平扫,6 例患者出现多发斑块及大片实变,3 例患者出现多发斑片状巩固及斑片状磨玻璃影,3 例患者出现单发或多发结节及肿块,3 例患者多发空洞和小结节。10 例患者双侧纵隔、颈部出现多发淋巴结肿大。CT增强扫描显示病灶实质有轻度强化 10 例,中度强化 3 例,明显强化 2 例。骨质破坏和增生 7 例,颅骨受累 1 例,肝脏受累 3 例。在PET/CT上,5 例患者显示标准摄取值 (SUV) 升高。非HIV距骨真菌病的放射学表现表现为多发性巩固性、磨玻璃影、双侧肺部多发结节或肿块、深部肿大淋巴结及多系统骨质破坏。最终诊断应基于距骨真菌病的培养。

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