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Cardiovascular Implications in Patients Infected with Covid-19 and the Importance of Social Isolation to Reduce Dissemination of the Disease.

新型冠状病毒肺炎感染患者的心血管影响以及社会隔离对减少疾病传播的重要性。

  • 影响因子:1.00
  • DOI:10.36660/abc.20200243
  • 作者列表:"Costa JA","Silveira JA","Santos SCMD","Nogueira PP
  • 发表时间:2020-06-01
Abstract

:Respiratory symptoms, especially the development of severe acute respiratory distress syndrome, dominate the discussion and initial concerns of the population and health professionals. However, the cardiovascular system is greatly affected by these conditions and is often responsible for complications and mortality of these patients. In order to show the cardiovascular implications in patients infected with COVID-19 and the importance of social isolation as an alternative to curb the spread of the disease, a literature review was carried out based on 37 articles, in English, Portuguese and Spanish, available on Scielo and PubMed. The findings showed that cardiac complications associated with COVID-19 infection are similar to those produced by: severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS) and influenza. However, COVID-19 has a much greater and faster contamination and, unlike influenza, there is no vaccine or treatment available yet. In view of this, social isolation becomes a tool that can reduce and flatten the curve of cases and thus protect the people at higher risk, decreasing the chances of serious conditions related to the disease, potential deaths and the collapse of the country's health system. :Os sintomas respiratórios, principalmente o desenvolvimento de quadros de síndrome do desconforto respiratório agudo grave, dominam a discussão e as preocupações iniciais da população e dos profissionais de saúde. Entretanto, o sistema cardiovascular é bastante afetado por essas condições e, muitas vezes, é o responsável por complicações e mortalidade desses pacientes. Com o objetivo de mostrar as implicações cardiovasculares em pacientes infectados pela COVID-19 e a importância do isolamento social como alternativa de frear a disseminação da doença, foi realizada uma revisão da literatura com base em 37 artigos, nos idiomas inglês, português e espanhol, disponíveis na plataforma Scielo e PubMed. Os resultados mostraram que complicações cardíacas associadas à infecção pela COVID-19 são semelhantes às produzidas por: síndrome respiratória aguda grave (SARS), síndrome respiratória do Médio Oriente (MERS) e influenza. Contudo, a COVID-19 apresenta uma contaminação muito maior e mais rápida e, ao contrário da gripe por influenza, ainda não existe vacina disponível ou tratamento. Diante disso, o isolamento social passa a ser uma ferramenta que pode reduzir e achatar a curva de casos incidentes e assim preservar as pessoas que se enquadrem no grupo de risco, diminuindo as chances de quadros graves da doença, possíveis óbitos e o colapso no sistema de saúde do país.

摘要

: 呼吸系统症状,特别是严重急性呼吸窘迫综合征的发展,主导了人口和卫生专业人员的讨论和最初关注。然而,心血管系统很大程度上受到这些条件的影响,往往负责这些患者的并发症和死亡率。为了显示新型冠状病毒肺炎感染患者的心血管影响,以及社会隔离作为遏制疾病传播的替代方法的重要性,基于 37 篇文献进行了文献综述,英语、葡萄牙语和西班牙语版本,可在Scielo和PubMed上获得。研究结果表明,心脏并发症新型冠状病毒肺炎感染相似出品: 严重急性呼吸系统综合症 (传染性非典型肺炎),中东呼吸综合征流感.然而,新型冠状病毒肺炎的污染要快得多,而且与流感不同,目前还没有可用的疫苗或治疗方法。有鉴于此,社会隔离成为一种工具,可以减少和拉平病例曲线,从而保护高风险人群,减少与疾病相关的严重疾病的机会,潜在的死亡和国家卫生系统的崩溃。 : Os sintomas respirat ó rios,principalmente o desenvolvimento de quadros de s í ndrome do descenconforto respirat ó rio agudo grave,dominam a discsane as presend ocapis inicais da population a ó o e dos propiionais de sad ú de.Entretanto,o sistema cardiovascular é bastante afetado por essas condition ç es e,muitas vezes,é o respons á vel por complex ç es e mortalidade dess pacientes.Com o objectivo de mostrar as cardicardiasovculares em pacientes infecatados pela新型冠状病毒肺炎e a important-ncia do isolamento social como alternativa de frear a transpiration a ç o da doen ç a,foi realizada uma revisao da ó a com base artiem 37 artigos,nos idiomas ingl è s,portugu è s e espanhol,disponi í veis na plataforma Scielo e PubMed。Os resultados mostraram que complicações cardíacas associadas à infecção pela新型冠状病毒肺炎《semelhantes às produzidas por: síndrome respiratória aguda grave (传染性非典型肺炎),síndrome respiratória做Médio Oriente,涉及电子流感.Condudo,a新型冠状病毒肺炎apresenta uma poloma ç o muito maior e mais r á pida e,ao contru á rio da gripe por influenza,ainda n ão exive vacina disponi vel ou tratamento.Diante disso,o isolamento social passa a ser uma ferramenta que pode reduzir e achtar a curva de casos incidenes e assim presvar as pessoas que se enquadrem no grupo de risco,diminuindo as chance de quadros graves da doen ç a,pose í veis ó bitos e o colapso no sistema de sa ú de do pa í s.

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METHODS::Since mid-December of 2019, coronavirus disease 2019 (COVID-19) infection has been spreading from Wuhan, China. The confirmed COVID-19 patients in South Korea are those who came from or visited China. As secondary transmissions have occurred and the speed of transmission is accelerating, there are rising concerns about community infections. The 54-year old male is the third patient diagnosed with COVID-19 infection in Korea. He is a worker for a clothing business and had mild respiratory symptoms and intermittent fever in the beginning of hospitalization, and pneumonia symptoms on chest computerized tomography scan on day 6 of admission. This patient caused one case of secondary transmission and three cases of tertiary transmission. Hereby, we report the clinical findings of the index patient who was the first to cause tertiary transmission outside China. Interestingly, after lopinavir/ritonavir (Kaletra, AbbVie) was administered, β-coronavirus viral loads significantly decreased and no or little coronavirus titers were observed.

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翻译标题与摘要 下载文献
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DOI:10.1007/s15010-020-01401-y
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METHODS::There is a current worldwide outbreak of a new type of coronavirus (2019-nCoV), which originated from Wuhan in China and has now spread to 17 other countries. Governments are under increased pressure to stop the outbreak spiraling into a global health emergency. At this stage, preparedness, transparency, and sharing of information are crucial to risk assessments and beginning outbreak control activities. This information should include reports from outbreak sites and from laboratories supporting the investigation. This paper aggregates and consolidates the virology, epidemiology, clinical management strategies from both English and Chinese literature, official news channels, and other official government documents. In addition, by fitting the number of infections with a single-term exponential model, we report that the infection is spreading at an exponential rate, with a doubling period of 1.8 days.

呼吸道感染方向

呼吸道感染分为上呼吸道感染与下呼吸道感染。上呼吸道感染是指自鼻腔至喉部之间的急性炎症的总称,是最常见的感染性疾病。下呼吸道感染是最常见的感染性疾患,治疗时必须明确引起感染的病原体以选择有效的抗生素。

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