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BBMRI-ERIC's contributions to research and knowledge exchange on COVID-19.

BBMRI-ERIC对新型冠状病毒肺炎研究和知识交流的贡献。

  • 影响因子:3.36
  • DOI:10.1038/s41431-020-0634-8
  • 作者列表:"Holub P","Kozera L","Florindi F","van Enckevort E","Swertz M","Reihs R","Wutte A","Valík D","Mayrhofer MT","BBMRI-ERIC community.
  • 发表时间:2020-06-01
Abstract

:During the COVID-19 pandemic, the European biobanking infrastructure is in a unique position to preserve valuable biological material complemented with detailed data for future research purposes. Biobanks can be either integrated into healthcare, where preservation of the biological material is a fork in clinical routine diagnostics and medical treatment processes or they can also host prospective cohorts or material related to clinical trials. The paper discussed objectives of BBMRI-ERIC, the European research infrastructure established to facilitate access to quality-defined biological materials and data for research purposes, with respect to the COVID-19 crisis: (a) to collect information on available European as well as non-European COVID-19-relevant biobanking resources in BBMRI-ERIC Directory and to facilitate access to these via BBMRI-ERIC Negotiator platform; (b) to help harmonizing guidelines on how data and biological material is to be collected to maximize utility for future research, including large-scale data processing in artificial intelligence, by participating in activities such as COVID-19 Host Genetics Initiative; (c) to minimize risks for all involved parties dealing with (potentially) infectious material by developing recommendations and guidelines; (d) to provide a European-wide platform of exchange in relation to ethical, legal, and societal issues (ELSI) specific to the collection of biological material and data during the COVID-19 pandemic.

摘要

: 在新型冠状病毒肺炎大流行期间,欧洲生物样本库基础设施处于独特的地位,可以保存有价值的生物材料,并补充详细的数据用于未来的研究目的。生物样本库可以整合到医疗保健中,其中生物材料的保存是临床常规诊断和医疗过程的一个分支,或者它们也可以主办与临床试验相关的前瞻性队列或材料。本文讨论了BBMRI-ERIC的目标,该欧洲研究基础设施的建立是为了促进获得高质量的生物材料和数据用于研究目的,关于新型冠状病毒肺炎危机 :( a)收集关于BBMRI-ERIC目录中可用的欧洲和非欧洲COVID-19-relevant生物样本资源的信息,并促进通过BBMRI-ERIC谈判平台访问这些资源; (b) 为了帮助协调关于如何收集数据和生物材料的指导方针,以最大限度地提高未来研究的效用,包括人工智能中的大规模数据处理,通过参与新型冠状病毒肺炎宿主遗传学倡议等活动; (c) 通过制定建议和准则,最大限度地减少处理 (可能) 传染性材料的所有相关方的风险; (d) 提供与道德、法律和社会问题相关的欧洲范围的交流平台 (ELSI)特别是在新型冠状病毒肺炎大流行期间收集生物材料和数据。

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翻译标题与摘要 下载文献
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呼吸道感染方向

呼吸道感染分为上呼吸道感染与下呼吸道感染。上呼吸道感染是指自鼻腔至喉部之间的急性炎症的总称,是最常见的感染性疾病。下呼吸道感染是最常见的感染性疾患,治疗时必须明确引起感染的病原体以选择有效的抗生素。

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