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In and Beyond COVID-19: US Academic Pharmaceutical Science and Engineering Community Must Engage to Meet Critical National Needs.

在新型冠状病毒肺炎和超越: 美国学术制药科学和工程界必须参与,以满足关键的国家需求。

  • 影响因子:2.60800
  • DOI:10.1208/s12249-020-01718-9
  • 作者列表:"Gurvich VJ","Hussain AS
  • 发表时间:2020-05-24
Abstract

:The supply of affordable, high-quality pharmaceuticals to US patients has been on a critical path for decades. In and beyond the COVID-19 pandemic, this critical path has become tortuous. To regain reliability, reshoring of the pharmaceutical supply chain to the USA is now a vital national security need. Reshoring the pharmaceutical supply with old know-how and outdated technologies that cause inherent unpredictability and adverse environmental impact will neither provide the security we seek nor will it be competitive and affordable. The challenge at hand is complex akin to redesigning systems, including corporate and public research and development, manufacturing, regulatory, and education ones. The US academic community must be engaged in progressing solutions needed to counter emergencies in the COVID-19 pandemic and in building new methods to reshore the pharmaceutical supply chain beyond the pandemic.

摘要

: 几十年来,向美国患者供应负担得起的高质量药品一直处于关键阶段。在新型冠状病毒肺炎大流行之后,这一关键道路变得曲折。为了重新获得可靠性,将药品供应链重新固定到美国现在是一项至关重要的国家安全需求。用导致固有的不可预测性和不利环境影响的旧的专门技术和过时的技术来重新配置药品供应,既不会提供我们寻求的安全性,也不会具有竞争力和负担得起。手头的挑战很复杂,类似于重新设计系统,包括企业和公共研发、制造、监管和教育系统。美国学术界必须致力于制定应对新型冠状病毒肺炎大流行突发事件所需的解决方案,并制定新的方法,在大流行之外重新支撑药品供应链。

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呼吸道感染方向

呼吸道感染分为上呼吸道感染与下呼吸道感染。上呼吸道感染是指自鼻腔至喉部之间的急性炎症的总称,是最常见的感染性疾病。下呼吸道感染是最常见的感染性疾患,治疗时必须明确引起感染的病原体以选择有效的抗生素。

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