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Associations between untraditional risk factors, pneumonia/lung cancer, and hospital fatality among hypertensive men in Guangzhou downtown.

广州市中心城区高血压男性非传统危险因素、肺炎/肺癌与医院病死率之间的关系。

  • 影响因子:4.29
  • DOI:10.1038/s41598-020-58207-z
  • 作者列表:"Shen Y","Chen Y","Huang Z","Huang J","Li X","Tian Z","Li J
  • 发表时间:2020-01-29
Abstract

:Mortality of primary hypertension is high worldwide. Whether untraditional factors exist in modern life and affect the mortality is not well studied. The aim of the study was to evaluate the risk factors for fatality rate of hypertensive men in downtown area. A cross-sectional study was performed on hypertensive men, who were hospitalized into our hospital and lived in eligible urban areas. The characteristics of the patients and factors for the fatality were analyzed and of the risks or the contributors on the status were investigated. 14354 patients were identified. Mean age was 68.9 ± 12.4 year old (y) and dead ones was 75.9 ± 9.5 y. The overall hospitalized fatality was 5.9%, which was increased with age: fatality with 0.7%, 2.2%, 2.9%, 7.1%, 11.1% and 16.6% was for age group ≦ 49 y, 50-59 y, 60-69 y, 70-79 y, 80-89 y and ≧ 90 y respectively. The increased fatality was significantly positively correlated with the incidence of pneumonia, P < 0.05, r = 0.99. Pneumonia was prone to involve in men with older age and severer organ damage by hypertension. Similar to traditional risks such as coronary heart disease and stroke, pneumonia and lung cancer were also significantly associated with the fatality. Odds ratio (95% CI) for pneumonia and lung cancer were 6.18 (4.35-8.78) and 1.55 (1.14-2.11). The study provides evidence that pneumonia and lung cancer are highly associated with fatality of hypertensive men in downtown area, indicating that in order to reduce the fatality of hypertension, these lung diseases should be prevented and treated intensively in modern life.

摘要

: 原发性高血压的死亡率在世界范围内很高。现代生活中是否存在非传统因素并影响死亡率,目前研究较少。本研究的目的是评估中心地区高血压男性死亡率的危险因素。对入住我院并居住在符合条件的城市地区的高血压男性进行横断面研究。分析患者的特征和死亡因素,并调查风险或状态的贡献者。确定了 14354 例患者。平均年龄为 68.9   ± 12.4 岁,死亡者为 75.9   ± 9.5  。总住院死亡率为 5.9%,随年龄增加而增加: 死亡率为 0.7%,2.2%,2.9%,7.1%,11.1% 和 16.6%,年龄组 ≦≦49 y y,50-59 y y,60-69  y,70-79  y,80-89  y and ≧  90  y.病死率增加与肺炎发生率呈显著正相关,p <0.05,r = 0.99。肺炎易累及年龄较大、高血压所致器官损害较严重的男性。与冠心病和中风等传统风险相似,肺炎和肺癌也与病死率显著相关。肺炎和肺癌的比值比 (95% CI) 分别为 6.18 (4.35-8.78) 和 1.55 (1.14-2.11)。研究提供的证据表明,肺炎和肺癌与市中心地区高血压男性的病死率高度相关,表明为了降低高血压的病死率,在现代生活中,这些肺部疾病应该得到预防和治疗。

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影响因子:6.93
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翻译标题与摘要 下载文献
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DOI:10.1002/ijc.32530
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肺肿瘤,又叫支气管肺癌,是常见的恶性肿瘤之一。肺肿瘤的治疗为包括手术、中药、放疗、化疗及免疫等多学科的综合治疗。

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