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Marijuana use and health behaviors in a US clinic sample of patients with sickle cell disease.

美国镰状细胞病患者临床样本中的大麻使用和健康行为。

  • 影响因子:3.02
  • DOI:10.1371/journal.pone.0235192
  • 作者列表:"Wilson JD","Pecker LH","Lanzkron S","Bediako SM","Han D","Beach MC
  • 发表时间:2020-07-14
Abstract

INTRODUCTION:As marijuana use becomes more common, it is essential clinicians understand the relationship between marijuana use and health behaviors. METHODS:Using a retrospective cohort of adolescents and adults with sickle cell disease (SCD) stratified into a young (<25 years) and older cohort (> = 25 years), we conducted multiple linear regression examining relationship of marijuana use (independent variable) on each dependent variable (SCD self-management score and pain management). RESULTS:Among young cohort, 16.9% used marijuana compared to 21.8% of older cohort. The younger cohort reporting marijuana use had lower mean self-care scores (β = -2.74;p = 0.009) and were more likely to have admissions to the hospital for pain (β = 0.87;p = 0.047) compared to non-users. In contrast, the older cohort reporting marijuana use had more days treating pain at home (β = 0.44;p = 0.035). CONCLUSIONS:Only a minority of patients with SCD reported lifetime marijuana use. Among those reporting marijuana use, there were different associations with self-care and health-related behaviors by age. The older cohort who endorsed marijuana use reported more days of treating pain at home, although this did not translate into increased acute care visits for pain crisis. Among youth, endorsing marijuana use was associated with worse SCD self-care.

摘要

简介: 随着大麻的使用变得越来越普遍,临床医生必须了解大麻使用与健康行为之间的关系。 方法: 使用青少年和成人镰状细胞病 (SCD) 的回顾性队列,分为年轻 (<25岁) 和老年队列 (> = 25岁),我们进行了多重线性回归检查大麻使用的关系 (自变量) 对每个因变量 (SCD自我管理评分和疼痛管理)。 结果: 在年轻队列中,16.9% 使用大麻,而老年队列为21.8%。报告大麻使用的年轻队列与非使用者相比,平均自我护理得分较低 (β = -2.74;p = 0.009),并且更有可能因疼痛住院 (β = 0.87;p = 0.047)。相反,报道大麻使用的老年队列在家中治疗疼痛的天数更多 (β = 0.44;p = 0.035)。 结论: 只有少数SCD患者报告终生使用大麻。在报告使用大麻的人中,年龄与自我护理和健康相关行为有不同的关联。支持使用大麻的老年队列报告了更多的在家治疗疼痛的天数,尽管这并没有转化为疼痛危机的急性护理访视增加。在年轻人中,支持使用大麻与更糟糕的SCD自我护理有关。

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