- 作者列表："Sayseng V","Grondin J","Weber RA","Konofagou E
:Unfocused ultrasound imaging, particularly coherent compounding with diverging waves, is a commonly employed high-frame rate transmit strategy in cardiac strain imaging. However, the accuracy and precision of diverging wave imaging compared to focused-beam transmit approaches in human subjects is unknown. Three transmit strategies-coherent compounding imaging, composite focused imaging with ECG gating and narrow-beams, and focused imaging with wide-beams-were compared in simulation and in transthoracic imaging of healthy human subjects (n = 7). The focused narrow-beam sequence estimated radial end-systolic cumulative strains of a simulated left ventricular deformation with 26% ± 1.5% and 34% ± 1.5% greater accuracy compared with compounding and wide-beam imaging, respectively. Strain estimation precision in transthoracic imaging was then assessed with the Strain Filter on cumulative end-systolic radial strains. Within the strain values where statistically significant differences in precision (E(SNRe|ε)) were found between transmit strategies, the narrow-beam sequence estimated radial strain 13% ± 0.71% and 34% ± 8.9% more precisely on average compared to compounding or wide-beam imaging, respectively.
: 非聚焦超声成像，特别是与发散波的相干复合，是心脏应变成像中常用的高帧率传输策略。然而，与人类受试者中的聚焦波束传输方法相比，发散波成像的准确性和精确度是未知的。三种传输策略-相干复合成像，ECG门控和窄光束的复合聚焦成像，以及宽光束的聚焦成像-在健康人体受试者的模拟和经胸成像中进行了比较 (n = 7)。聚焦窄束序列估计模拟左心室变形的径向收缩末期累积应变，与复合和宽束成像相比，准确度分别提高了26% ± ± 1.5% 34% 1.5% 和 ± ± 。然后用应变滤波器对累积收缩末期径向应变评估经胸成像中的应变估计精度。在传输策略之间发现精度 (E(SNRe | Ε)) 在统计上显著差异的应变值中，窄束序列估计径向应变13% ± ± 0.71% 34% 和8.9% ± ε ，平均比复合或宽束成像更精确。
METHODS::We present the case of a 61-year-old woman with a large tumoral infiltration extending from the pelvis throughout the inferior vena cava inferior to the right atrium, protruding into the right ventricle and right ventricular outflow tract. She had been treated 10 years before for low-grade endometrial stromal sarcoma by hysterectomy and adnexectomy followed by hormone- and radio-therapy. Due to cancer recurrence, she underwent peritonectomy, appendectomy, and resection of terminal ileum.
METHODS:AIMS:Significant platelet activation after long stented coronary segments has been associated with periprocedural microvascular impairment and myonecrosis. In long lesions treated either with an everolimus-eluting bioresorbable vascular scaffold (BVS) or an everolimus-eluting stent (EES), we aimed to investigate (a) procedure-related microvascular impairment, and (b) the relationship of platelet activation with microvascular function and related myonecrosis. METHODS AND RESULTS:Patients (n=66) undergoing elective percutaneous coronary intervention (PCI) in long lesions were randomised 1:1 to either BVS or EES. The primary endpoint was the difference between groups in changes of pressure-derived corrected index of microvascular resistance (cIMR) after PCI. Periprocedural myonecrosis was assessed by high-sensitivity cardiac troponin T (hs-cTnT), platelet reactivity by high-sensitivity adenosine diphosphate (hs-ADP)-induced platelet reactivity with the Multiplate Analyzer. Post-dilatation was more frequent in the BVS group, with consequent longer procedure time. A significant difference was observed between the two groups in the primary endpoint of ΔcIMR (p=0.04). hs-ADP was not different between the groups at different time points. hs-cTnT significantly increased after PCI, without difference between the groups. CONCLUSIONS:In long lesions, BVS implantation is associated with significant acute reduction in IMR as compared with EES, with no significant interaction with platelet reactivity or periprocedural myonecrosis.
METHODS:BACKGROUND:Aortopulmonary window is an uncommon congenital heart disease, with untreated cases not surviving beyond childhood. However, very rarely it can present in adult patients with features of pulmonary hypertension. Clinically these patients cannot be differentiated from other more common conditions with left to right shunt. Transthoracic echocardiography if performed meticulously, can depict the defect in aortopulmonary septum. RESULTS:We report a case of large unrepaired aortopulmonary window in a 23 years old patient, diagnosed on transthoracic echocardiography.