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Acute rupture of a sinus of Valsalva aneurysm into the right atrium: a case report and a narrative review.

主动脉窦瘤急性破裂进入右心房: 病例报告和叙述回顾。

  • 影响因子:2.06
  • DOI:10.1186/s12872-020-01383-7
  • 作者列表:"Doost A","Craig JA","Soh SY
  • 发表时间:2020-02-18
Abstract

BACKGROUND:Sinus of Valsalva aneurysm (SVA) is a rare cardiac anomaly which has potential for spontaneous rupture into other cardiac chambers or the pericardial space (depending on its location). A ruptured SVA has a very poor prognosis with high morbidity and mortality. The development of a shunt between the sinus of Valsalva and right-sided cardiac chambers results in a continuous murmur on examination. Our case report is a case of SVA rupture into the right atrium. CASE PRESENTATION:In this case report, we describe a 23-year-old patient with an acute onset of chest pain, shortness of breath, palpitations and dizziness starting 2 days prior to presentation to the emergency department. The patient was initially treated for presumed pulmonary embolism overnight while awaiting CTPA the next morning. However, further examination by the inpatient medical team demonstrated a continuous machinery cardiac murmur. Subsequent echocardiography demonstrated an acutely ruptured SVA with shunting to the right atrium. Emergency surgical repair resulted in an excellent outcome for the patient. CONCLUSION:A thorough clinical history and physical examination is the cornerstone of all medical encounters. An SVA could be asymptomatic until acute rupture. Echocardiography is the preferred initial diagnostic tool. Additional imaging techniques can be used to confirm the diagnosis. In cases of rupture, prognosis is poor and surgical repair is always required.

摘要

背景: 主动脉窦瘤 (SVA) 是一种罕见的心脏异常,有可能自发破裂进入其他心腔或心包间隙 (取决于其位置)。破裂的SVA具有非常差的预后,具有高发病率和死亡率。Valsalva窦和右侧心腔之间的分流的发展导致在检查时出现连续的杂音。我们的病例报告是一例SVA破裂进入右心房。 病例报告: 在本病例报告中,我们描述了一名23岁的患者,在急诊就诊前2天开始急性发作胸痛、气短、心慌和头晕。在第二天早上等待CTPA的同时,患者最初治疗假定的肺栓塞过夜。然而,住院医疗小组的进一步检查显示连续的机械性心脏杂音。随后的超声心动图显示SVA急性破裂并分流至右心房。紧急手术修复为患者带来了极好的结果。 结论: 彻底的临床病史和体格检查是所有医学遭遇的基石。SVA可能无症状,直到急性破裂。超声心动图是首选的初始诊断工具。可以使用额外的成像技术来确认诊断。在破裂的情况下,预后差,总是需要手术修复。

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DOI:10.1002/jcu.22732
作者列表:["Tadic M","Belyavskiy E","Cuspidi C","Pieske B","Haßfeld S"]

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影响因子:2.41
发表时间:2020-06-12
DOI:10.4244/EIJ-D-18-01138
作者列表:["Pellicano M","Di Gioia G","Ciccarelli G","Xaplanteris P","Delrue L","Toth GG","Van Durme F","Heyse A","Wyffels E","Vanderheyden M","Bartunek J","De Bruyne B","Barbato E"]

METHODS:AIMS:Significant platelet activation after long stented coronary segments has been associated with periprocedural microvascular impairment and myonecrosis. In long lesions treated either with an everolimus-eluting bioresorbable vascular scaffold (BVS) or an everolimus-eluting stent (EES), we aimed to investigate (a) procedure-related microvascular impairment, and (b) the relationship of platelet activation with microvascular function and related myonecrosis. METHODS AND RESULTS:Patients (n=66) undergoing elective percutaneous coronary intervention (PCI) in long lesions were randomised 1:1 to either BVS or EES. The primary endpoint was the difference between groups in changes of pressure-derived corrected index of microvascular resistance (cIMR) after PCI. Periprocedural myonecrosis was assessed by high-sensitivity cardiac troponin T (hs-cTnT), platelet reactivity by high-sensitivity adenosine diphosphate (hs-ADP)-induced platelet reactivity with the Multiplate Analyzer. Post-dilatation was more frequent in the BVS group, with consequent longer procedure time. A significant difference was observed between the two groups in the primary endpoint of ΔcIMR (p=0.04). hs-ADP was not different between the groups at different time points. hs-cTnT significantly increased after PCI, without difference between the groups. CONCLUSIONS:In long lesions, BVS implantation is associated with significant acute reduction in IMR as compared with EES, with no significant interaction with platelet reactivity or periprocedural myonecrosis.

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翻译标题与摘要 下载文献
影响因子:1.67
发表时间:2020-01-01
DOI:10.2174/1573403X15666190513105231
作者列表:["Dev M","Sharma M","Rana N"]

METHODS:BACKGROUND:Aortopulmonary window is an uncommon congenital heart disease, with untreated cases not surviving beyond childhood. However, very rarely it can present in adult patients with features of pulmonary hypertension. Clinically these patients cannot be differentiated from other more common conditions with left to right shunt. Transthoracic echocardiography if performed meticulously, can depict the defect in aortopulmonary septum. RESULTS:We report a case of large unrepaired aortopulmonary window in a 23 years old patient, diagnosed on transthoracic echocardiography.

心脏影像技术方向

心脏结构和心脏血流的可视化,用于诊断评估或通过内窥镜、放射性核素成像等技术来指导心脏手术。

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