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Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges.

恰加斯心肌病的运动试验: 功能评估、预后意义和当前挑战的概述。

  • 影响因子:0
  • DOI:10.1590/0037-8682-0100-2020
  • 作者列表:"Costa HS","Lima MMO","Figueiredo PHS","Lima VP","Ávila MR","Menezes KKP","Mendonça VA","Lacerda ACR","Nunes MCP","Mediano MFF","Rocha MODC
  • 发表时间:2020-01-01
Abstract

:Patients with Chagas cardiomyopathy (ChC) usually progress with fatigue and dyspnea. Exercise tests are valuable for the functional evaluation of these patients. However, information about the applicability of the exercise tests is scattered, and no studies have systematically reviewed the results. Thus, the present review explored the general aspects and prognostic value of exercise tests in patients with ChC. A literature search of the MEDLINE, Web of Science, CINAHL, Scopus, and LILACS databases was performed to identify relevant studies. There were no data restrictions, and articles that met the objective of the study were selected. Articles written in English, Portuguese, and Spanish were considered, and 25 articles were finally included. The peak oxygen uptake (VO2peak) was correlated with demographic and echocardiographic variables. Echocardiographic features of the left ventricular diastolic function and right ventricular systolic function appeared to be determinants of functional capacity, in addition to age and sex. VO2peak was associated with higher mortality, especially in patients with dilated ChC. The minute ventilation/carbon dioxide production slope (VE/VCO2 slope) was a strong predictor of survival; however, more studies are needed to verify this observation. Field tests showed moderate to strong correlation with VO2peak and thus may be inexpensive tools for the functional evaluation of patients with ChC. However, few studies have verified their prognostic significance. While exercise tests are useful tools for functional assessment, information is scarce regarding further considerations, and many of the criteria are based on guidelines for other heart diseases.

摘要

: Chagas心肌病 (ChC) 患者通常进展乏力和呼吸困难。运动试验对于这些患者的功能评估是有价值的。然而,有关运动试验适用性的信息是分散的,并且没有研究系统地审查结果。因此,本综述探讨了运动试验在ChC患者中的一般方面和预后价值。对MEDLINE、Web of Science、CINAHL、Scopus和LILACS数据库进行文献检索,以确定相关研究。没有数据限制,并选择符合研究目的的文章。考虑了用英语、葡萄牙语和西班牙语写的文章,最终纳入了25篇文章。峰值摄氧量 (VO2peak) 与人口统计学和超声心动图变量相关。除年龄和性别外,左心室舒张功能和右心室收缩功能的超声心动图特征似乎是功能能力的决定因素。VO2peak与较高的死亡率相关,特别是在扩张的ChC患者中。分钟通气量/二氧化碳产生斜率 (VE/VCO2斜率) 是生存的强预测因子; 然而,需要更多的研究来验证这一观察结果。现场试验显示与VO2peak有中度到强烈的相关性,因此可能是用于ChC患者功能评估的廉价工具。然而,很少有研究证实其预后意义。虽然运动测试是功能评估的有用工具,但是关于进一步考虑的信息很少,并且许多标准是基于其他心脏疾病的指南。

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影响因子:2.41
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关键词: 暂无
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影响因子:1.67
发表时间:2020-01-01
DOI:10.2174/1573403X15666190513105231
作者列表:["Dev M","Sharma M","Rana N"]

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心脏影像技术方向

心脏结构和心脏血流的可视化,用于诊断评估或通过内窥镜、放射性核素成像等技术来指导心脏手术。

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