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[Coronary artery disease in pre and postmenopausal women. The influence of type 2 diabetes mellitus].

[绝经前后妇女的冠状动脉疾病。2型糖尿病的影响]。

  • 影响因子:0
  • DOI:10.4067/s0034-98872020000200145
  • 作者列表:"Gajardo-Navarrete J","Ibieta G","Concha M","Garcés P","Robles I","Vera-Calzaretta A","González-Burboa A","Gajardo I","Gutiérrez M","Villarroel M","Aguayo M
  • 发表时间:2020-02-01
Abstract

BACKGROUND:Postmenopausal women have higher severity of coronary heart disease (CHD) than premenopausal women and type 2 diabetes mellitus (T2DM) is an independent risk factor. AIM:To assess the severity of CHD in pre and postmenopausal patients undergoing coronary angiography and the impact of T2DM in both groups. MATERIAL AND METHODS:A coronary angiography was performed to 707 women due to suspected CHD during 2013 and 2014. Of these, 579 were older than 55 years and were considered as postmenopausal. Factors such as hypertension, obesity, smoking, creatinine and T2DM were registered. The severity of CHD in coronary angiography was evaluated according to the number of vessels with more than 50% stenosis. RESULTS:Compared to their postmenopausal counterparts, premenopausal women had less frequency of T2DM (31% and 42% p < 0.033), hypertension (52 and 78%, p < 0.001) and alteration of renal function (11 vs. 39%, p < 0.001). Absence of coronary lesions was found in 44 and 32% of premenopausal and postmenopausal women, respectively (p < 0.01). Premenopausal women with T2DM had a higher frequency of multi-vessel disease than those without the disease (25 and 4.5%, p < 0.001). The frequency of multi-vessel disease was higher in postmenopausal than premenopausal women (24 and 11%, p < 0.01). Hypertension, T2DM and renal involvement were associated with a higher frequency multiple vessel disease. CONCLUSIONS:The severity of CHD is higher in postmenopausal women and T2DM is associated with the disease.

摘要

背景: 绝经后女性冠心病 (CHD) 的严重程度高于绝经前女性,2型糖尿病 (T2DM) 是其独立危险因素。 目的: 评估接受冠状动脉造影的绝经前后患者CHD的严重程度以及两组中T2DM的影响。 材料和方法: 在2013年和707年期间,对2014名因疑似CHD的女性进行了冠状动脉造影。其中,579的年龄大于55岁,被认为是绝经后的。记录高血压、肥胖、吸烟、肌酐和T2DM等因素。根据血管狭窄程度超过50% 的血管数量评估冠状动脉造影中CHD的严重程度。 结果: 与绝经后妇女相比,绝经前妇女发生T2DM (31% 和42%,p <0.033) 、高血压 (52和78%,p <0.001) 和肾功能改变 (11对39%,p <0.001) 的频率较低。在绝经前和绝经后妇女中,分别有44和32% 的人没有冠状动脉病变 (p <0.01)。绝经前女性T2DM患者多支血管病变发生率高于非绝经女性 (25和4.5%,p <0.001)。绝经后女性多支血管病变的发生率高于绝经前女性 (24和11%,p <0.01)。高血压、T2DM和肾脏受累与较高频率的多支血管病变相关。 结论: 绝经后女性CHD的严重程度较高,T2DM与疾病相关。

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影响因子:2.41
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DOI:10.4244/EIJ-D-18-01138
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关键词: 暂无
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影响因子:1.67
发表时间:2020-01-01
DOI:10.2174/1573403X15666190513105231
作者列表:["Dev M","Sharma M","Rana N"]

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心脏影像技术方向

心脏结构和心脏血流的可视化,用于诊断评估或通过内窥镜、放射性核素成像等技术来指导心脏手术。

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