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Prolonging gavage feeds for reduction of gastroesophageal reflux in infants.
延长灌胃饲料减少婴儿胃食管反流。
- 影响因子:2.23
- DOI:10.1038/s41372-020-0630-4
- 作者列表:"Favara MT","Abraham S","DiPalma J","Epstein M","Greenspan JS","Aghai ZH
- 发表时间:2020-02-21
Abstract
OBJECTIVE:To determine if prolonging gavage feedings in infants for ≥60 min is associated with decreased gastroesophageal reflux (GER) compared with bolus feeding using multiple-channel intraluminal impedance with pH probe (MII-pH). STUDY DESIGN:Retrospective analysis of infants who underwent MII-pH between October 2009 and July 2018 and received gavage feedings. Infants were divided into two groups: bolus (<30 min) or prolonged (≥60 min). Symptoms, number of reflux events and percent time pH < 4 was compared. RESULT:Fifty-eight infants underwent evaluation. Thirty-one (54%) received bolus gavage feedings and 27 (46%) received prolonged feedings. Groups differed in postmenstrual age. Total reflux episodes were significantly lower with prolonged feeding (median 19 vs. 28 episodes, p = 0.015), with no difference in acid exposure time. There was no significant difference in GER symptoms between the two groups. CONCLUSION:Prolongation of gavage feedings was associated with decreased total numbers of GER events without reduction in GER symptoms.
摘要
目的: 确定婴儿延长灌胃喂养 ≥ 60 分钟是否与胃食管反流 (GER) 减少有关。与使用具有pH探针的多通道腔内阻抗 (MII-pH) 的推注喂养相比。 研究设计: 回顾性分析 2009 年 10 月至 2018 年 7 月期间接受MII-pH并接受灌胃喂养的婴儿。婴儿分为两组: 推注 (<30 min) 或延长 (≥ 60 min)。比较症状、反流事件次数和ph <4 时间百分比。 结果: 58 例婴儿接受了评估。31 例 (54%) 接受大剂量灌胃喂养,27 例 (46%) 接受长时间喂养。各组经后年龄不同。总反流发作次数随喂养时间延长显著降低 (中位数 19 vs. 28 次,p = 0.015),酸暴露时间无差异。两组患者的GER症状差异无统计学意义。 结论: 灌胃喂养时间延长与GER事件总数减少有关,而GER症状不减少。
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