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^18F-FDG PET/CT findings of COVID-19: a series of four highly suspected cases
新型冠状病毒肺炎 ^ 18F-FDG PET/CT 四种高疑似病例
- 影响因子:5.36
- DOI:10.1007/s00259-020-04734-w
- 作者列表:"Qin, Chunxia","Liu, Fang","Yen, Tzu-Chen","Lan, Xiaoli
- 发表时间:2020-02-22
Abstract
Purpose The aim of this case series is to illustrate the ^18F-FDG PET/CT findings of patients with acute respiratory disease caused by COVID-19 in Wuhan, Hubei province of China. Methods We describe the ^18F-FDG PET/CT results from four patients who were admitted to the hospital with respiratory symptoms and fever between January 13 and January 20, 2020, when the COVID-19 outbreak was still unrecognized and the virus infectivity was unknown. A retrospective review of the patients’ medical history, clinical and laboratory data, as well as imaging findings strongly suggested a diagnosis of COVID-19. Results All patients had peripheral ground-glass opacities and/or lung consolidations in more than two pulmonary lobes. Lung lesions were characterized by a high ^18F-FDG uptake and there was evidence of lymph node involvement. Conversely, disseminated disease was absent, a finding suggesting that COVID-19 has pulmonary tropism. Conclusions Although ^18F-FDG PET/CT cannot be routinely used in an emergency setting and is generally not recommended for infectious diseases, our pilot data shed light on the potential clinical utility of this imaging technique in the differential diagnosis of complex cases.
摘要
目的探讨湖北省武汉市新型冠状病毒肺炎所致急性呼吸系统疾病的 18F-FDG PET/CT 表现。方法对 1月13日至 2020年1月20日因呼吸道症状和发热入院的 4 例患者的 ^ 18F-FDG PET/CT 结果进行描述。当新型冠状病毒肺炎的爆发仍然无法识别,病毒的传染性也未知。回顾性分析患者的病史、临床和实验室资料,以及影像学检查结果,强烈提示诊断为新型冠状病毒肺炎。结果所有患者均出现周边磨玻璃影和/或两个以上肺叶的肺巩固。肺部病变的特征是 ^ 18F-FDG 高摄取,并有淋巴结受累的证据。相反,播散性疾病是不存在的,这表明新型冠状病毒肺炎有肺嗜性。结论虽然 ^ 18F-FDG PET/CT 不能常规用于急诊,一般不推荐用于感染性疾病。我们的试验数据揭示了这种成像技术在复杂病例鉴别诊断疾病中的潜在临床效用。
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