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Measurement of intrapleural pressure in patients with spontaneous pneumothorax: a pilot study

自发性气胸患者胸腔内压测定的初步研究

  • 影响因子:2.40
  • DOI:10.1186/s12890-019-1038-9
  • 作者列表:"Hiroyuki Kaneda","Takahito Nakano","Tomohiro Murakawa
  • 发表时间:2020-01-05
Abstract

Abstract Background The initial management of pneumothorax remains controversial, and we speculated that this might be because there is no method available for evaluation of air leak during initial management. We have developed a system for measurement of intrapleural pressure in pneumothorax to address air leak without the need for chest drainage. The aim of this clinical study was to confirm the ability of this measurement system and to determine the clinical impact of management of air leak. Methods Patients in whom need aspiration was indicated for spontaneous pneumothorax were enrolled in the study. The intrapleural pressure was measured during stable breathing and data recorded when patients were coughing were excluded. Results Eleven patients were enrolled in the study between December 2016 to July 2017. The patterns in change of intrapleural pressure varied widely depending on the state of the pneumothorax. The mean intrapleural pressure values on end-inspiration and end-expiration in patients with persistent air leak was significantly lower than those in patients without persistent air leak (p = 0.020). The number of negative mean pressure recordings in end-inspiration and end-expiration was significantly lower in patients with persistent air leak than in those without persistent air leak (p = 0.0060). Conclusions In this study, we demonstrated that intrapleural pressure could be successfully measured and visualized in patients with pneumothorax. Whether or not the pressure value is a predictor of persistent air leak needs to be confirmed in the future.

摘要

摘要背景气胸的初始管理仍存在争议,我们推测这可能是因为在初始管理期间没有可用于评估空气泄漏的方法。我们开发了一种测量气胸中胸腔内压的系统,以解决漏气而不需要胸腔引流。本临床研究的目的是证实该测量系统的能力,并确定空气泄漏管理的临床影响。方法自发性气胸需抽吸的患者纳入研究。稳定呼吸时测量胸膜内压,排除患者咳嗽时记录数据。结果 2016年12月至 2017年7月期间,11 例患者入选研究。胸膜腔内压的变化规律因气胸的状态而异。持续漏气患者吸气末和呼气末的平均胸膜内压值明显低于无持续漏气患者 (p = 0.020)。持续漏气患者吸气末和呼气末的负压记录数量显著低于无持续漏气患者 (p = 0.0060)。结论在这项研究中,我们证明了在气胸患者中可以成功地测量和显示胸腔内压。压力值是否是持续漏气的预测因子,需要在将来确认。

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影响因子:3.94
发表时间:2020-01-15
DOI:10.1016/j.taap.2019.114847
作者列表:["Bernstein DM","Toth B","Rogers RA","Kling DE","Kunzendorf P","Phillips JI","Ernst H"]

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影响因子:4.04
发表时间:2020-01-10
DOI:10.1042/BST20191010
作者列表:["Zaragosi LE","Deprez M","Barbry P"]

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