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Fire Needle Therapy for the Treatment of Psoriasis: A Quantitative Evidence Synthesis.

火针疗法治疗银屑病: 定量证据综合。

  • 影响因子:1.75
  • DOI:10.1089/acm.2019.0409
  • 作者列表:"Liu L","Sun XY","Lu Y","Song JK","Xing M","Chen X","Luo Y","Ru Y","Chen ST","Li HJ","Li B","Li X
  • 发表时间:2021-01-01
Abstract

: Background: Fire needle therapy is a method of quickly piercing into acupoints with red-hot needles to treat diseases. Recently, multiple studies have reported that fire needle therapy is effective in the treatment of psoriasis; however, there are few articles systematically evaluating the effect of this therapy. Therefore, this systematic and meta-analysis study is conducted to estimate the efficacy and safety of fire needle therapy for psoriasis. Methods: PubMed, Embase, CNKI, VIP, CBM, CENTRAL, and Wan Fang databases were systematically searched from the dates of construction of these databases to August 24, 2019, and randomized controlled trials assessing patients with psoriasis who were treated with fire needle therapy alone or in combination with other drugs were also evaluated. Results: Fire needle therapy was effective in treating psoriasis (p = 0.0002; risk ratio [RR], 1.20; 95% confidence interval [CI], 1.09-1.33) with a lower recurrence rate (p = 0.005; RR, 0.48; 95% CI, 0.29-0.80). Adverse events after fire needle treatment were similar to those without fire needle treatment (p = 0.38; RR, 0.67; 95% CI, 0.28-1.63). After fire needle treatment, the number of cluster of differentiation (CD)8+T cells, type 1 helper cells, interleukin (IL)-2, and interferon (IFN)-γ decreased, whereas the number of CD4+T cells, type 2 helper cells, IL-4, IL-10, and the proportion of CD4+T cells and CD8+T cells increased. Conclusions: Fire needle therapy, specifically in combination with oral medicines, is effective in treating patients with psoriasis with low recurrence rates.

摘要

: 背景: 火针疗法是用炽热的针快速刺入穴位治疗疾病的方法。最近,多项研究报道火针疗法对银屑病的治疗有效; 然而,很少有文章系统地评价这种疗法的效果。因此,本系统荟萃分析研究旨在评估火针治疗银屑病的疗效和安全性。 方法: 系统检索PubMed、Embase、CNKI、VIP、CBM、CENTRAL、Wan Fang数据库从这些数据库的建库日期至2019年8月24日,并对评估单独使用火针疗法或与其他药物联合治疗的银屑病患者的随机对照试验进行评价。 结果: 火针疗法治疗银屑病有效 (p = 0.0002; 风险比 [RR],1.20; 95% 可信区间 [CI],1.09-1.33),复发率较低 (p = 0.005; RR,0.48; 95% CI,0.29-0.80)。火针治疗后的不良事件与未使用火针治疗的不良事件相似 (p   =   0.38; RR,0.67; 95% CI,0.28-1.63)。火针治疗后,分化簇 (CD)8 + T细胞、1型辅助细胞、白细胞介素 (IL)-2、干扰素 (IFN)-γ 数量减少,而CD4 + T细胞、2型辅助细胞、IL-4、IL-10、且CD4 + T细胞和CD8 + T细胞比例增高。 结论: 火针疗法,特别是与口服药物相结合,可有效治疗复发率低的银屑病患者。

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