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Establishing an endoscopic diagnostic process system (M-system) for gastric MALT lymphoma of superficial-spreading type.

建立浅表扩散型胃MALT淋巴瘤内镜诊断流程系统 (M-system)。

  • 影响因子:0
  • DOI:10.1093/jjco/hyaa242
  • 作者列表:"Peng T","Deng L","Wang Y","Wang R","Zeng F","Xie M","Gou X","Guo Y","Wu D","Peng F","Gao R","Ye X
  • 发表时间:2021-04-01
Abstract

OBJECTIVE:Gastric mucosa-associated lymphoid tissue lymphoma is a rare disease, which is associated with a low endoscopic diagnostic accuracy even on tissue biopsy. We aimed to establish a diagnostic process system (M-system) using detailed magnifying endoscopy images to improve the diagnostic efficiency of this disease. METHODS:First, 34 cases from 16 patients with the diagnosis of mucosa-associated lymphoid tissue lymphoma were collected as the study group. The control group included randomly selected patients who were diagnosed with early differentiated carcinoma, undifferentiated carcinoma or inflammation. Then, the endoscopic images of these patients were analyzed by senior physicians. Finally, the M-system was established based on the data extracted from the images reviewed, and its diagnostic efficiency for mucosa-associated lymphoid tissue lymphoma was validated by the junior physicians. RESULTS:A series of elements with high sensitivity and specificity for the diagnosis of mucosa-associated lymphoid tissue lymphoma on endoscopic images were extracted for the establishment of the M-system. Using the M-system, the diagnostic accuracy, sensitivity, specificity and correct indices of mucosa-associated lymphoid tissue lymphoma rose from 65.4 to 79.4%, 41.2 to 76.5%, 73.5 to 80.4% and 0.147 to 0.569%, respectively, all of which were statistically significant. CONCLUSIONS:The M-system can improve the diagnostic accuracy of mucosa-associated lymphoid tissue lymphoma of the superficial-spreading type on detailed magnifying endoscopy. This would help in the early diagnosis of the disease and treatment, which would translate into improved clinical outcomes.

摘要

目的: 胃粘膜相关淋巴组织淋巴瘤是一种罕见的疾病,即使在组织活检上,也与内镜诊断准确性低有关。我们的目的是建立一个诊断过程系统 (M系统) 使用详细的放大内镜图像,以提高这种疾病的诊断效率。 方法: 首先,收集16例黏膜相关淋巴组织淋巴瘤患者34例作为研究组。对照组随机选择确诊为早期分化癌、未分化癌或炎症的患者。然后,由高级医师分析这些患者的内镜图像。最后,根据所回顾的图像中提取的数据建立了M-系统,并由初级医师验证了其对黏膜相关淋巴组织淋巴瘤的诊断效率。 结果: 提取了一系列内镜图像上诊断黏膜相关淋巴组织淋巴瘤的敏感性和特异性较高的元素,用于建立M-系统。使用M-系统,黏膜相关淋巴组织淋巴瘤的诊断准确率、敏感性、特异性和正确指标分别从65.4上升到79.4% 、41.2上升到76.5% 、73.5上升到80.4% 、0.147上升到0.569%,均有统计学意义。 结论: M-系统在详细放大内镜下可提高浅表扩散型黏膜相关淋巴组织淋巴瘤的诊断准确率。这将有助于疾病的早期诊断和治疗,这将转化为改善的临床结果。

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