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Chondrosesamoidean ligament enthesopathy: Prevalence and findings in a population of lame horses imaged with positron emission tomography.

软骨病韧带病变: 正电子发射断层扫描成像的跛足马人群的患病率和发现。

  • 影响因子:1.86
  • DOI:10.1111/evj.13299
  • 作者列表:"Norvall A","Spriet M","Espinosa P","Ariño-Estrada G","Murphy BG","Katzman SA","Galuppo LD
  • 发表时间:2021-05-01
Abstract

BACKGROUND:Increased 18 F-Sodium Fluoride (18 F-NaF) uptake at the chondrosesamoidean ligament (ChSL) attachment on the distal phalanx was identified in an exploratory positron emission tomography (PET) study. The prevalence and significance of this lesion has not been previously investigated. OBJECTIVES:The goal of this study was to assess the prevalence of this lesion, its association with other imaging findings and with clinical signs. STUDY DESIGN:Retrospective cross-sectional analytical study. METHODS:All horses with 18 F-NaF PET and computed tomography (CT) imaging of the feet performed between October 2016 and December 2017 were included in the study. All PET scans were independently assessed by two radiologists for increased uptake at the ChSL attachment site and concurrent imaging was reviewed. Clinical findings, treatment and outcome were retrieved from the medical records. RESULTS:Fourteen of 30 horses (20/56 feet) had increased 18 F-NaF uptake in the region of interest. ChSL enthesopathy was the primary lesion in three horses. Other PET abnormalities included navicular bone uptake (13 feet) and ipsilateral palmar process uptake (9 feet). There was no significant association between ChSL enthesopathy and other lesions. ChSL enthesopathy was significantly associated with foot lameness. CT abnormalities at the ChSL attachment were initially identified in one foot, and retrospectively noted in another five following the results of PET imaging. MAIN LIMITATIONS:The study is retrospective and there was a limited sample size. CONCLUSIONS:PET led to identification of ChSL enthesopathy in a large proportion of horses with foot pain. This finding is most commonly associated with other lesions but may also represent the main abnormality. The axial border of the palmar processes of the distal phalanx should be carefully assessed on cross sectional imaging to identify this lesion. ChSL enthesopathy may be an important but previously not recognised component of foot pathology in horses.

摘要

背景: 在一项探索性的正电子发射断层扫描 (PET) 研究中发现,远端指骨软骨骨韧带 (ChSL) 附着处的18 F-氟化钠 (18 F-NaF) 摄取增加。以前没有研究过这种病变的患病率和意义。 目的: 本研究的目的是评估该病变的患病率,其与其他影像学表现和临床体征的相关性。 研究设计: 回顾性横断面分析研究。 方法: 所有在2016年10月至2017年12月期间进行了18 F-NaF PET和足部计算机断层扫描 (CT) 成像的马均纳入研究。由两名放射科医师独立评估所有PET扫描在ChSL附着部位的摄取增加,并审查同时成像。从医疗记录中检索临床发现、治疗和结果。 结果: 30匹马中的14匹 (20/56英尺) 在感兴趣区域中增加了18 F-NaF摄取。3匹马的原发病灶为ChSL病灶。其他PET异常包括舟状骨摄取 (13英尺) 和同侧掌突摄取 (9英尺)。ChSL病变与其他病变无明显相关性。ChSL病变与足部跛行显著相关。在1英尺中最初发现了ChSL附件处的CT异常,并在PET成像结果之后的另外五个中回顾性地注意到。 主要局限性: 本研究是回顾性研究,样本量有限。 结论: PET导致在大部分患有足部疼痛的马中鉴别出ChSL病变。这一发现最常与其他病变相关,但也可能代表主要异常。远端指骨掌突的轴向边界应在横断面成像上仔细评估以识别该病变。ChSL附件病可能是马足部病变的重要但以前未识别的组成部分。

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