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NUT Midline Carcinoma of the Lung: Computed Tomography Findings in 10 Patients.

肺坚果中线癌: 10例患者的计算机断层扫描结果。

  • 影响因子:1.48
  • DOI:10.1097/RCT.0000000000001133
  • 作者列表:"Chang AI","Kim TS","Han J","Kim TJ","Choi JY
  • 发表时间:2021-03-01
Abstract

OBJECTIVE:The aim of the study was to evaluate computed tomography (CT) findings of pulmonary NUT midline carcinoma. METHODS:We assessed clinical and CT features of pulmonary NUT carcinoma in 10 consecutive patients (M:F, 7:3; mean, 39 years). RESULTS:The primary tumors (size range, 15-65 mm) manifested as either a peripheral tumor (5/10) or a central tumor (5/10). All tumors showed relatively low-attenuation at contrast-enhanced CT (mean net enhancement, 26 HU). Associated CT findings were metastatic hilar or mediastinal lymphadenopathy (8/10), ipsilateral pleural seeding with malignant pleural effusion (2/10), and distant metastasis (2/10). Five patients with low tumor-node-metastasis stages after optimal treatment showed no evidence of disease (50%) for 6 to 35 months. CONCLUSIONS:Pulmonary NUT carcinoma presented as a peripheral or a central lung mass showing mild degree of contrast enhancement, frequent metastatic regional lymphadenopathy, affecting relatively young adults. Although known to be highly aggressive, an early diagnosis in low TNM stages can lead to a favorable prognosis.

摘要

目的: 探讨肺坚果中线癌的CT表现。 方法: 我们评估了10例 (M:F,7:3; 平均,39岁) 的肺癌的临床和CT特征。 结果: 原发肿瘤 (大小范围,15-65毫米) 表现为外周肿瘤 (5/10) 或中心肿瘤 (5/10)。所有肿瘤在对比增强CT (平均净增强,26 hu) 中显示相对低的衰减。相关CT表现为肺门或纵隔淋巴结转移 (8/10),同侧胸膜种植伴恶性胸腔积液 (2/10) 和远处转移 (2/10)。在最佳治疗后的低肿瘤淋巴结转移阶段的5例患者 (50%) 在6至35个月内未显示疾病证据。 结论: 肺坚果癌表现为周围或中心肺肿块,显示轻度对比增强,频繁转移性区域淋巴结肿大,影响相对年轻的成年人。虽然已知具有高度侵袭性,但在低TNM分期中的早期诊断可导致良好的预后。

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