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Electrophysiological correlates of visual backward masking in patients with bipolar disorder.

双相情感障碍患者视觉反向掩蔽的电生理相关性。

  • 影响因子:2.70
  • DOI:10.1016/j.pscychresns.2020.111206
  • 作者列表:"Garobbio S","Roinishvili M","Favrod O","da Cruz JR","Chkonia E","Brand A","Herzog MH
  • 发表时间:2021-01-30
Abstract

:In visual backward masking (VBM), a target is followed by a mask that decreases target discriminability. Schizophrenia patients (SZ) show strong and reproducible masking impairments, which are associated with reduced EEG amplitudes. Patients with bipolar disorder (BP) show masking deficits, too. Here, we investigated the neural EEG correlates of VBM in BP. 122 SZ, 94 unaffected controls, and 38 BP joined a standard VBM experiment. 123 SZ, 94 unaffected controls and 16 BP joined a corresponding EEG experiment, analyzed in terms of global field power. As in previous studies, SZ and BP show strong masking deficits. Importantly and similarly to SZ, BP show decreased global field power amplitudes at approximately 200 ms after the target onset, compared to controls. These results suggest that VBM deficits are not specific for schizophrenia but for a broader range of functional psychoses. Potentially, both SZ and BP show deficient target enhancement.

摘要

: 在视觉反向掩蔽 (VBM) 中,目标之后是降低目标可辨性的掩蔽。精神分裂症患者 (SZ) 表现出强烈且可重复的掩蔽损伤,这与EEG振幅降低有关。双相情感障碍 (BP) 患者也表现出掩蔽缺陷。在这里,我们研究了BP中VBM的神经脑电图相关性。122个SZ、94个未受影响的对照和38个BP加入标准VBM实验。123个SZ、94个未受影响的对照和16个BP加入了相应的EEG实验,根据全局场功率进行了分析。与之前的研究一样,SZ和BP显示强掩蔽缺陷。重要的是,与SZ类似,与对照相比,BP在目标开始后约200 ms处显示出降低的全局场功率振幅。这些结果表明VBM缺陷不是精神分裂症的特异性,而是更广泛的功能性精神病。潜在地,SZ和BP都显示缺乏的靶标增强。

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影响因子:2.68
发表时间:2021-02-01
DOI:10.1080/14656566.2020.1814255
作者列表:["Sawada H","Oeda T","Kohsaka M","Tomita S","Umemura A","Park K","Yamamoto K","Kiyohara K"]

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发表时间:2021-03-24
DOI:10.1007/s11033-021-06299-9
作者列表:["Louvrier A","Terranova L","Meyer C","Meyer F","Euvrard E","Kroemer M","Rolin G"]

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